Detailed information NTG0082748

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H7674_RS06920
• Genome accession: NZ_AP023388
• Coordinates: 1415141..1416142 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NIH35
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1410141..1421142

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7674_RS06905 (SPNIH35_13180)	thrS	1410311..1412254 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
H7674_RS06910 (SPNIH35_13190)	-	1412676..1414010 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
H7674_RS06915 (SPNIH35_13200)	-	1414012..1415010 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
H7674_RS06920 (SPNIH35_13210)	ccpA	1415141..1416142 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
H7674_RS06925 (SPNIH35_13220)	-	1416316..1417401 (+)	1086	WP_011284589.1	aminopeptidase P family protein	-
H7674_RS06930 (SPNIH35_13230)	-	1417450..1418115 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
H7674_RS06935 (SPNIH35_13240)	-	1418126..1418503 (+)	378	WP_002985686.1	VOC family protein	-
H7674_RS06940 (SPNIH35_13250)	-	1418648..1419574 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
H7674_RS06945 (SPNIH35_13260)	-	1419785..1420468 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=82748 H7674_RS06920 WP_002985680.1 1415141..1416142(-) (ccpA) [Streptococcus pyogenes strain NIH35]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=82748 H7674_RS06920 WP_002985680.1 1415141..1416142(-) (ccpA) [Streptococcus pyogenes strain NIH35]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559