Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   R8507_RS09340 Genome accession   NZ_AP026925
Coordinates   1809810..1811318 (-) Length   502 a.a.
NCBI ID   WP_317643199.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700097     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1804810..1816318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8507_RS09315 (PC0094_18330) - 1805549..1806880 (-) 1332 WP_000390042.1 hemolysin family protein -
  R8507_RS09320 (PC0094_18340) endA 1807171..1807995 (-) 825 WP_001036783.1 DNA-entry nuclease EndA Machinery gene
  R8507_RS09325 (PC0094_18350) - 1808034..1808222 (-) 189 WP_001812859.1 DNA-directed RNA polymerase subunit beta -
  R8507_RS09330 (PC0094_18360) murA 1808215..1809498 (-) 1284 WP_000358027.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R8507_RS09335 (PC0094_18370) - 1809522..1809752 (-) 231 WP_001809307.1 DUF1146 family protein -
  R8507_RS09340 (PC0094_18380) sepM 1809810..1811318 (-) 1509 WP_317643199.1 SepM family pheromone-processing serine protease Regulator
  R8507_RS09345 (PC0094_18390) rsmD 1811308..1811847 (-) 540 WP_044788620.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R8507_RS09350 (PC0094_18400) asnA 1811912..1812904 (-) 993 WP_044791888.1 aspartate--ammonia ligase -
  R8507_RS09355 (PC0094_18410) - 1813015..1813698 (-) 684 WP_001016917.1 Bax inhibitor-1/YccA family protein -
  R8507_RS09360 (PC0094_18420) - 1813754..1814494 (-) 741 WP_044791890.1 RNA methyltransferase -
  R8507_RS09365 (PC0094_18430) - 1814528..1814806 (+) 279 WP_001174613.1 acylphosphatase -
  R8507_RS09370 (PC0094_18440) yidC 1814884..1815810 (+) 927 WP_000835941.1 membrane protein insertase YidC -

Sequence

Protein


Download         Length: 502 a.a.        Molecular weight: 55369.81 Da        Isoelectric Point: 5.6514

>NTDB_id=82720 R8507_RS09340 WP_317643199.1 1809810..1811318(-) (sepM) [Streptococcus pneumoniae strain PZ900700097]
MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKAVKHLGNVKVVSSHDELVVDVA
KRLGATCLVRGLRNASDLQYEASFDYYNHQLSPDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
KIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIR
SAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTFDSS
KDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSLAIY
TQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIK
TDMKIVPVKTLQDAIDYLKNNP

Nucleotide


Download         Length: 1509 bp        

>NTDB_id=82720 R8507_RS09340 WP_317643199.1 1809810..1811318(-) (sepM) [Streptococcus pneumoniae strain PZ900700097]
ATGTCAGATAAGATTGGCTTATTCACAGGCTCATTTGATCCGATGACAAATGGGCATCTGGATATCATTGAACGGGCGAG
CAGACTCTTTGATAAGCTCTATGTCGGTATTTTTTTTAATCCCCACAAACAAGGATTTCTTCCTATCGAAAATCGTAAAC
GGGGGTTAGAAAAGGCTGTGAAACATTTGGGAAATGTTAAAGTCGTGTCTTCTCATGATGAATTGGTGGTCGATGTCGCA
AAAAGACTGGGGGCTACTTGCCTAGTGCGAGGCTTGAGAAATGCGTCGGATTTGCAATACGAAGCCAGTTTTGATTACTA
CAACCATCAGCTGTCTCCTGATATAGAGACTATTTATTTACATAGTCGACCTGAACATCTCTATATCAGTTCATCAGGCG
TTAGAGAGCTTTTGAAGTTTGGTCAGGATATTGCCTGCTATGTTCCCGAGAGTATTTTGGAGGAAATAAGAAATGAAAAA
AAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTGGTGCCTTTGCCCTACTATAT
AGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTGGTGCCTATC
AATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACAGATATTCGT
AGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAACATCGCAAAA
TATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTTTGAATGTGA
CGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTTGATAGTTCC
AAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGGGCAAACCAA
GTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTACAGAGGTAA
TCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTAGCTATCTAT
ACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGGTAATGTGGG
AGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTGATAACCCTG
TTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAAACAATCAAG
ACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterProScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(387-453)

PDZ domain (PDZ_2)

(287-350)

Cytidylyltransferase-like (CTP_transf_like)

(7-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

58.96

68.924

0.406

Multiple sequence alignment