Detailed information NTG0826353

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: QJV49_RS10690
• Genome accession: NZ_CP124538
• Coordinates: 2105296..2107746 (+)
• Length: 816 a.a.
• NCBI ID: WP_225511589.1
• Uniprot ID: A0AA49EVC3
• Organism: Lactococcus sp. NH2-7C
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2100296..2112746

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QJV49_RS10665 (QJV49_10665)	-	2101064..2101576 (+)	513	WP_012897343.1	adenine phosphoribosyltransferase	-
QJV49_RS10670 (QJV49_10670)	rpoE	2101790..2102353 (+)	564	WP_225511587.1	DNA-directed RNA polymerase subunit delta	-
QJV49_RS10675 (QJV49_10675)	mltG	2102490..2104142 (+)	1653	WP_225511588.1	endolytic transglycosylase MltG	-
QJV49_RS10680 (QJV49_10680)	greA	2104201..2104674 (+)	474	WP_025016857.1	transcription elongation factor GreA	-
QJV49_RS10685 (QJV49_10685)	-	2104851..2105306 (+)	456	WP_058209439.1	CtsR family transcriptional regulator	-
QJV49_RS10690 (QJV49_10690)	clpC	2105296..2107746 (+)	2451	WP_225511589.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
QJV49_RS10695 (QJV49_10695)	hpf	2107881..2108438 (+)	558	WP_225511590.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
QJV49_RS10700 (QJV49_10700)	eno	2108625..2109926 (+)	1302	WP_225511591.1	surface-displayed alpha-enolase	-
QJV49_RS10705 (QJV49_10705)	-	2110040..2110711 (-)	672	WP_225511592.1	ABC transporter ATP-binding protein	-
QJV49_RS10710 (QJV49_10710)	-	2110714..2111787 (-)	1074	WP_225511593.1	ABC transporter permease	-
QJV49_RS10715 (QJV49_10715)	-	2111799..2112368 (-)	570	WP_225511594.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90453.86 Da
• Isoelectric Point: 6.5300

>NTDB_id=826353 QJV49_RS10690 WP_225511589.1 2105296..2107746(+) (clpC) [Lactococcus sp. NH2-7C]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINLVSLRKELEKRTGLKVPESKKAVTPMSK
RKMAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQAKRLDLEKELFEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNLIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=826353 QJV49_RS10690 WP_225511589.1 2105296..2107746(+) (clpC) [Lactococcus sp. NH2-7C]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTATGCTCACCAATATCA
ATATGGCACTATTGAAAGTGCTCATTTATTGGCAGCAATGGCTACGACTTCAGGCTCAATTGCTTACAGCCTTCTTGCTG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTTAAACGCTCAACTTTA
CGTTTTTCACCACGTGCAGAAGAAGTGATGACTGCGGCAAGCTTTTTAGCAATTCATAACAACTCAGAAGCCGTTGGAAC
AGAACACTTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTAAAATTGCAAAAAATCAATCTTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTAAAAGTTCCAGAAAGTAAAAAAGCTGTGACCCCAATGTCAAAA
CGCAAGATGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACATTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGTTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCAGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGCTTGGCCCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTCTGATGAATAGTCGGATTATGGCTTTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGCGAATTTGAAGACCGTTTGACAGCTATCGTTGAGGAAGTCAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATCGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCGAATATTTTGAAACCTGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGATGAGCCAAGTCCAGATGAAGCGATTGCCATTTTACAAGGCTTGCGTGAAAAATTTGAAG
ATTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACTAGTCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCGGTGAAAATTTCTGTCAAAAATCAACAAGCAAAACG
TCTTGATTTAGAAAAAGAATTATTTGAAGCTCAAGAAGAATTATCAGAAGCGGTCATTAAACTTGACATCAAAGCATCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACACAAACGGGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGAGCGCGTTCTGGTGTTGCTGACAGCCGTCGTCCAATGGGGTCTTTCATGTTCCTCGGACCAACAGGGGTCGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGCGTATTTGGTAGTGAAGATAATCTGATTCGTGTTGATATGAGTGAATTCAT
GGAAAAACATTCAACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GTGTTCGTAATAAACCTTATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCGGATGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGATTTGTGACTGATACTAAAGGCCGCAAAGTTGATTTCAGAAATACAATTATTATTATGACTTC
AAACTTGGGAGCGACAGCGCTCCGTGATGATAAGACAGTTGGCTTTGGCGCTAAAAATATTACAGCTGATTATTCAGCCA
TGAAATCAAGAATTTTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CATTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATAATGAGCAAATCTTTGATTAAACGTTTGGCAGAACAAGA
TATTCATGTTAAACTCACACCGTCAGCGGTGAAATTAATTGCTGAAGTAGGCTTTGACCCAGAATATGGTGCACGTCCGC
TACGTAAAGCACTTCAAAAAGAAGTTGAAGACCTTTTAAGTGAACAACTCCTTTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGTGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• AAA lid domain (AAA_lid_9) (357-453)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	99.51	100	0.995
clpC	Streptococcus thermophilus LMD-9	50.542	100	0.515
clpC	Streptococcus thermophilus LMG 18311	50.421	100	0.513
clpC	Streptococcus pneumoniae D39	48.918	100	0.499
clpC	Streptococcus pneumoniae Rx1	48.918	100	0.499
clpC	Streptococcus mutans UA159	48.798	100	0.498
clpC	Streptococcus pneumoniae TIGR4	48.798	100	0.498
clpC	Bacillus subtilis subsp. subtilis str. 168	50.499	98.284	0.496
clpE	Streptococcus mutans UA159	47.692	79.657	0.38
clpC	Lactococcus lactis subsp. cremoris KW2	46.718	80.27	0.375
clpE	Streptococcus pneumoniae TIGR4	47.528	76.838	0.365
clpE	Streptococcus pneumoniae Rx1	47.528	76.838	0.365
clpE	Streptococcus pneumoniae D39	47.528	76.838	0.365
clpE	Streptococcus pneumoniae R6	47.528	76.838	0.365