Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   M2Y46_RS04385 Genome accession   NZ_AP023347
Coordinates   923439..925223 (+) Length   594 a.a.
NCBI ID   WP_248415109.1    Uniprot ID   -
Organism   Helicobacter pylori strain JSHR6     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 918439..930223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2Y46_RS04350 (JSHR6_08670) motA 918504..919277 (+) 774 WP_000366185.1 flagellar motor stator protein MotA -
  M2Y46_RS04355 (JSHR6_08680) motB 919280..920047 (+) 768 WP_001085307.1 flagellar motor protein MotB -
  M2Y46_RS04360 (JSHR6_08690) - 920051..920488 (+) 438 WP_001031792.1 hypothetical protein -
  M2Y46_RS04365 (JSHR6_08700) - 920593..922149 (+) 1557 WP_248415107.1 ABC transporter permease/substrate-binding protein -
  M2Y46_RS04370 (JSHR6_08710) - 922153..922794 (+) 642 WP_248415108.1 ABC transporter ATP-binding protein -
  M2Y46_RS04375 - 922806..922985 (-) 180 WP_000468796.1 hypothetical protein -
  M2Y46_RS04380 (JSHR6_08720) - 922977..923438 (+) 462 WP_050828325.1 hypothetical protein -
  M2Y46_RS04385 (JSHR6_08730) uvrC 923439..925223 (+) 1785 WP_248415109.1 excinuclease ABC subunit UvrC Machinery gene
  M2Y46_RS04390 (JSHR6_08740) - 925234..926499 (+) 1266 WP_248415110.1 homoserine dehydrogenase -
  M2Y46_RS04395 (JSHR6_08750) - 926500..926844 (+) 345 WP_154443339.1 YraN family protein -
  M2Y46_RS04400 (JSHR6_08760) trxA 926933..927253 (+) 321 WP_000020199.1 thioredoxin -
  M2Y46_RS04405 (JSHR6_08770) trxB 927259..928194 (+) 936 WP_248415111.1 thioredoxin-disulfide reductase -
  M2Y46_RS04410 (JSHR6_08780) - 928361..929182 (+) 822 WP_248415112.1 glycosyltransferase family 25 protein -
  M2Y46_RS04415 (JSHR6_08790) - 929386..929634 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68741.17 Da        Isoelectric Point: 9.7488

>NTDB_id=82493 M2Y46_RS04385 WP_248415109.1 923439..925223(+) (uvrC) [Helicobacter pylori strain JSHR6]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNCRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNEMLKELQEFISHQYSKKIALSIPKKGNKLALIEIAMKNAQKIFSQEKTSNEDLILEEAQSLFKLECMPYRVEIFDV
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=82493 M2Y46_RS04385 WP_248415109.1 923439..925223(+) (uvrC) [Helicobacter pylori strain JSHR6]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATTGTCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTAGAAAACGAACAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAACAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAATATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGATAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATAGTGGGAACAATAAGGCGGT
ATTAGTGAAGATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCAGAACAGATTTTATTGAAC
GCTTGTTCTAATGAAATGCTTAAAGAATTGCAAGAATTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCAATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAAAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCAATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGTA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTATGGGTGATCGATGGAGGGAGAGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCCTATCGCTCTAAAGGGGGTGCTAAAGACATTAT
CCACACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGTGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAAGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.633

100

0.966

Multiple sequence alignment