Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   R8625_RS09595 Genome accession   NZ_AP026923
Coordinates   1848380..1848643 (-) Length   87 a.a.
NCBI ID   WP_000962025.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1843380..1853643
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS09550 (PC0054_18580) rnpA 1843398..1843769 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8625_RS09555 - 1843786..1843917 (-) 132 WP_000768904.1 hypothetical protein -
  R8625_RS09560 (PC0054_18590) - 1843918..1845108 (-) 1191 WP_000167769.1 acetate kinase -
  R8625_RS09565 (PC0054_18600) comGH 1845159..1846112 (-) 954 WP_317649157.1 class I SAM-dependent methyltransferase Machinery gene
  R8625_RS09570 - 1846173..1846767 (-) 595 Protein_1857 class I SAM-dependent methyltransferase -
  R8625_RS09575 (PC0054_18630) comGG/cglG 1846870..1847316 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8625_RS09580 (PC0054_18640) comGF/cglF 1847294..1847755 (-) 462 WP_000250523.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8625_RS09585 (PC0054_18650) comGE/cglE 1847718..1848020 (-) 303 WP_317649158.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8625_RS09590 (PC0054_18660) comGD/cglD 1847983..1848417 (-) 435 WP_000608686.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8625_RS09595 (PC0054_18670) comGC/cglC 1848380..1848643 (-) 264 WP_000962025.1 competence type IV pilus major pilin ComGC Machinery gene
  R8625_RS09600 (PC0054_18680) - 1848645..1848902 (-) 258 WP_000698511.1 hypothetical protein -
  R8625_RS09605 (PC0054_18690) - 1849173..1850129 (-) 957 WP_219601358.1 N-acetylmuramoyl-L-alanine amidase family protein -
  R8625_RS09610 (PC0054_18700) - 1850133..1850465 (-) 333 WP_050085269.1 phage holin -
  R8625_RS09615 (PC0054_18710) - 1850469..1850768 (-) 300 WP_001811580.1 hypothetical protein -
  R8625_RS09620 (PC0054_18720) - 1850777..1851127 (-) 351 WP_000852245.1 hypothetical protein -
  R8625_RS09625 (PC0054_18730) - 1851130..1851333 (-) 204 WP_001091109.1 hypothetical protein -
  R8625_RS09630 - 1851314..1851430 (-) 117 WP_001063633.1 hypothetical protein -

Sequence


Protein


Download         Length: 87 a.a.        Molecular weight: 9877.37 Da        Isoelectric Point: 5.8577

>NTDB_id=82483 R8625_RS09595 WP_000962025.1 1848380..1848643(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700054]
MLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQDDGRITEEQAKAYKEYHDKQN
TSQIVKD

Nucleotide


Download         Length: 264 bp        

>NTDB_id=82483 R8625_RS09595 WP_000962025.1 1848380..1848643(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700054]
ATGTTGGTGGTCTTGCTGATTATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAA
TGACAAAGGAAAAGCAGCTGTTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTA
GCCTAAGAAAGTTACAAGACGATGGACGCATCACGGAAGAACAGGCTAAAGCCTATAAAGAATACCATGATAAACAAAAT
ACTAGTCAAATCGTTAAAGATTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

93.902

94.253

0.885

  comGC/cglC Streptococcus pneumoniae D39

93.902

94.253

0.885

  comGC/cglC Streptococcus pneumoniae R6

93.902

94.253

0.885

  comGC/cglC Streptococcus pneumoniae TIGR4

92.683

94.253

0.874

  comGC/cglC Streptococcus mitis NCTC 12261

91.781

83.908

0.77

  comGC/cglC Streptococcus mitis SK321

85.294

78.161

0.667

  comGC Streptococcus gordonii str. Challis substr. CH1

68.293

94.253

0.644

  comGC Streptococcus suis isolate S10

66.667

82.759

0.552

  comGC Streptococcus mutans UA140

61.905

72.414

0.448

  comGC Streptococcus mutans UA159

61.905

72.414

0.448

  comGC Lactococcus lactis subsp. cremoris KW2

50

80.46

0.402

  comGC Staphylococcus aureus MW2

46.377

79.31

0.368

  comGC Staphylococcus aureus N315

46.377

79.31

0.368


Multiple sequence alignment