Detailed information NTG0824796

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SE146_RS05575
• Genome accession: NZ_CP138339
• Coordinates: 1071929..1074502 (+)
• Length: 857 a.a.
• NCBI ID: WP_047926685.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain TH2288
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1066929..1079502

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SE146_RS05555 (SE146_05535)	-	1067654..1069162 (+)	1509	WP_050154454.1	Ppx/GppA phosphatase family protein	-
SE146_RS05560 (SE146_05540)	-	1069372..1069716 (-)	345	WP_048339613.1	Ag473 family lipoprotein	-
SE146_RS05565 (SE146_05545)	-	1070033..1070578 (-)	546	WP_003690987.1	hypothetical protein	-
SE146_RS05570 (SE146_05550)	trpS	1070659..1071669 (-)	1011	WP_003693403.1	tryptophan--tRNA ligase	-
SE146_RS05575 (SE146_05555)	clpC	1071929..1074502 (+)	2574	WP_047926685.1	ATP-dependent chaperone ClpB	Regulator
SE146_RS05580 (SE146_05560)	-	1074574..1075788 (-)	1215	WP_003695054.1	pyridoxal phosphate-dependent aminotransferase	-
SE146_RS05585 (SE146_05565)	-	1075877..1076086 (-)	210	WP_003688192.1	4-oxalocrotonate tautomerase family protein	-
SE146_RS05590 (SE146_05570)	-	1076278..1077084 (+)	807	WP_003704212.1	DUF4198 domain-containing protein	-
SE146_RS12085	-	1077144..1078363 (-)	1220	Protein_1095	Glu/Leu/Phe/Val family dehydrogenase	-
SE146_RS05605 (SE146_05585)	-	1078758..1079468 (+)	711	WP_003688188.1	phosphoglycolate phosphatase	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 94723.00 Da
• Isoelectric Point: 5.2460

>NTDB_id=824796 SE146_RS05575 WP_047926685.1 1071929..1074502(+) (clpC) [Neisseria gonorrhoeae strain TH2288]
MRYDKLTAKFQQALAEAQSLALAADSSYLEAGFVLKALLDDQNSGAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGE
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDAVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
IKMELDSKPEQMDKLDRRIIQLKMEKMHVAKESDDASKKRLELIDEEIDGLQKEYADLDEIWKAEKAASSSTADIKKQMD
DIKVKIEQAKRQGDFARASELEYGELPKLGAQLQAAESNPDGKKQNKLFRTEVGADEVAEIVSRMTGIPVSKMMEGERDK
LLKMEEVLHRRVVGQNEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSEYM
EKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPHSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTS
NIGSQHIQQMGTQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSDAA
LDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIKVEADGDRLKFA

Nucleotide

• Length: 2574 bp

>NTDB_id=824796 SE146_RS05575 WP_047926685.1 1071929..1074502(+) (clpC) [Neisseria gonorrhoeae strain TH2288]
ATGCGATACGACAAATTAACCGCCAAATTCCAACAAGCCCTTGCAGAAGCTCAGAGTTTGGCGTTGGCTGCGGACAGCAG
CTATCTGGAAGCAGGTTTCGTACTGAAAGCCCTGCTTGACGACCAAAACAGCGGAGCTGCCGCGCTCTTGGCTCATGCGG
GCGTGAACGTGCCGCAGGTTAAACAGCGTTTGCAGCAGCATTTGAACAGCCTGCCGAAAGTGTCCGGACAAGGTGGTGAG
ATTCTGCCCAGCCGCGAATTGCAGGCGGTGTTGAACCTGATGGACAAAGCGGCAACCAAACGCGGCGATGCCTATATCGC
CAGCGAACTTTTCCTGCTCGCCTTGGTGCAGCAGAACGATGCGGCCGGCAAAATCTTGAAAGAAGCCGGTGCGACCGAAC
AAAACATCAATGCCGCGATCGATGCGGTACGAGGCGGACAAAACGTGAACGATGCGAATGCCGAAGACCAACGCGATGCT
TTGAAAAAATACACGCTCGATCTGACCCAACGCGCCCGAGACGGTAAGCTCGACCCCGTTATCGGTCGTGATGATGAAAT
CCGCCGCGCGATTCAGGTGCTGCAACGCCGCACCAAAAACAACCCCGTGCTGATTGGCGAACCCGGTGTGGGTAAAACCG
CCATCGTCGAAGGTTTGGCGCAACGCATCGTCAACGGCGAAGTACCTGAATCCCTGCGTAACAAACGCCTGCTGGTTTTG
GATTTGGCGGCTTTGATTGCCGGTGCGAAATACCGTGGCGAATTTGAAGAACGCTTGAAAGGCGTATTGAACGATTTGGC
GAAAGACGACGGCAACACCCTGATTTTCATCGATGAAATCCATACTTTGGTCGGCGCGGGCAAAACCGACGGCGCGATGG
ACGCGGGCAATATGTTGAAACCGGCCTTGGCGCGGGGCGAACTGCACTGTATCGGTGCGACTACTTTGGACGAATACCGC
CAATACATCGAAAAAGACGCGGCACTCGAACGCCGTTTCCAAAAAGTATTGGTCGGCGAACCCAGCGTGGAAGACACCAT
CGCTATCCTGCGCGGTTTGCAGGAACGTTACGAAATCCACCACGGCATCGATATTACCGACCCTGCTATCGTTGCCGCAG
CGGAGTTGAGCGACCGCTACATTACCGACCGCTTTTTGCCCGACAAAGCGATTGATTTGATTGACGAAGCCGCCAGCCGC
ATCAAAATGGAGCTGGACAGCAAACCCGAACAGATGGACAAACTCGACCGCCGCATCATCCAGCTCAAAATGGAAAAAAT
GCACGTTGCCAAAGAAAGCGATGATGCCAGCAAAAAACGTTTGGAACTGATAGACGAAGAAATCGACGGCCTGCAAAAAG
AATACGCCGATTTGGACGAAATCTGGAAAGCCGAAAAAGCCGCGTCTTCCAGCACTGCCGACATCAAGAAACAAATGGAC
GACATCAAAGTCAAAATCGAACAAGCCAAACGTCAAGGCGACTTCGCCCGCGCGTCCGAACTCGAATACGGCGAGTTGCC
GAAATTGGGCGCACAGTTGCAGGCAGCGGAAAGCAACCCCGACGGCAAAAAACAAAACAAACTTTTCCGTACCGAAGTCG
GCGCGGATGAAGTGGCCGAAATCGTTTCCCGTATGACCGGCATTCCCGTATCCAAAATGATGGAAGGCGAACGCGATAAA
TTGTTGAAAATGGAAGAAGTGTTGCACCGCCGCGTAGTCGGTCAAAACGAAGCCGTGCGCGCCGTGTCCGATGCCATCCG
CCGCAGCCGCTCCGGCCTTGCCGATCCGAACAAACCTTACGGCAGCTTCCTGTTCTTAGGCCCGACCGGTGTGGGTAAGA
CCGAGTTGTGCAAAGCTTTGGCAGGCTTCCTGTTCGACAGCGAAGACCACCTCATCCGCATCGACATGTCCGAATACATG
GAAAAACACGCCGTTGCCCGCTTAATCGGCGCGCCTCCGGGTTATGTCGGATACGAAGAGGGCGGCTACCTGACCGAACA
AGTCCGCCGCAAACCGCACAGCGTGATTCTTTTGGACGAAGTGGAAAAAGCCCATCCCGACGTATTCAACATCCTGCTGC
AAGTATTGGATGACGGTCGTTTGACCGACGGACAAGGCAGGACGGTAGATTTTAAAAATACCGTGATTGTGATGACTTCC
AACATCGGCAGCCAGCACATCCAACAAATGGGCACGCAGGACTACGAAGCGGTGAAAGAAGTTGTGATGGAGGATGTGAA
AGAACATTTCCGTCCGGAAATGATCAACCGCATCGACGAAGTGGTCGTGTTCCATGGCTTGGATCAGGCCAATATCCGCA
GTATTGCGAAAATCCAGCTCAAAGGTTTGGAAAAACGTTTGGAAAAACAAAACCTGCGCCTGACTGTTTCCGATGCCGCT
CTGGACATCATCGCCAAAGCCGGTTTCGACCCGATTTACGGCGCACGTCCGCTCAAACGCGCGATCCAATCGGAAATCGA
AAACCCGCTGGCCAAAGCCCTGCTTGCCGGAAACTATGCGCCCGAAAGCGAAATCAAGGTAGAAGCCGACGGCGACAGAC
TGAAATTTGCCTGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (599-761)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (767-847)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• AAA lid domain (AAA_lid_9) (342-442)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.721	100	0.439
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.418	100	0.397
clpC	Lactococcus lactis subsp. cremoris KW2	44.524	80.98	0.361