Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   M2Y57_RS04465 Genome accession   NZ_AP023345
Coordinates   942409..944193 (+) Length   594 a.a.
NCBI ID   WP_248425572.1    Uniprot ID   -
Organism   Helicobacter pylori strain JSHR31     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 937409..949193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2Y57_RS04435 (JSHR31_08720) motB 938070..938837 (+) 768 WP_001085319.1 flagellar motor protein MotB -
  M2Y57_RS04440 (JSHR31_08730) - 938841..939278 (+) 438 WP_001031792.1 hypothetical protein -
  M2Y57_RS04445 (JSHR31_08740) - 939458..941119 (+) 1662 WP_248425571.1 ABC transporter permease/substrate-binding protein -
  M2Y57_RS04450 (JSHR31_08750) - 941123..941764 (+) 642 WP_025222907.1 ATP-binding cassette domain-containing protein -
  M2Y57_RS04455 - 941776..941955 (-) 180 WP_000468796.1 hypothetical protein -
  M2Y57_RS04460 (JSHR31_08760) - 941947..942408 (+) 462 WP_120836089.1 hypothetical protein -
  M2Y57_RS04465 (JSHR31_08770) uvrC 942409..944193 (+) 1785 WP_248425572.1 excinuclease ABC subunit UvrC Machinery gene
  M2Y57_RS04470 (JSHR31_08780) - 944204..945469 (+) 1266 WP_248425573.1 homoserine dehydrogenase -
  M2Y57_RS04475 (JSHR31_08790) - 945469..945813 (+) 345 WP_248425574.1 YraN family protein -
  M2Y57_RS04480 (JSHR31_08800) trxA 945902..946222 (+) 321 WP_000020199.1 thioredoxin -
  M2Y57_RS04485 (JSHR31_08810) trxB 946228..947163 (+) 936 WP_021301752.1 thioredoxin-disulfide reductase -
  M2Y57_RS04490 (JSHR31_08820) - 947330..948151 (+) 822 WP_248425575.1 glycosyltransferase family 25 protein -
  M2Y57_RS04495 (JSHR31_08830) - 948356..948604 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68577.82 Da        Isoelectric Point: 9.4806

>NTDB_id=82473 M2Y57_RS04465 WP_248425572.1 942409..944193(+) (uvrC) [Helicobacter pylori strain JSHR31]
MADLLSSLKNLSHSSGVYQYFDKNHQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMECLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGGNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDA
SHHANSQCVGGMVVYENHEFQKNSYRCYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=82473 M2Y57_RS04465 WP_248425572.1 942409..944193(+) (uvrC) [Helicobacter pylori strain JSHR31]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCACCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACCGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAAGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGTGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGGGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCACGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGCA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGTG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTACTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTGAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAACAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.633

100

0.966

Multiple sequence alignment