Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   M2Y48_RS04990 Genome accession   NZ_AP023344
Coordinates   1040057..1041841 (+) Length   594 a.a.
NCBI ID   WP_248419652.1    Uniprot ID   -
Organism   Helicobacter pylori strain JSHR3     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1035057..1046841
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2Y48_RS04960 (JSHR3_10230) motB 1035718..1036485 (+) 768 WP_001085311.1 flagellar motor protein MotB -
  M2Y48_RS04965 (JSHR3_10240) - 1036489..1036926 (+) 438 WP_001031792.1 hypothetical protein -
  M2Y48_RS04970 (JSHR3_10250) - 1037107..1038767 (+) 1661 Protein_987 ABC transporter permease/substrate-binding protein -
  M2Y48_RS04975 (JSHR3_10260) - 1038771..1039412 (+) 642 WP_212884454.1 ABC transporter ATP-binding protein -
  M2Y48_RS04980 - 1039424..1039603 (-) 180 WP_000468796.1 hypothetical protein -
  M2Y48_RS04985 (JSHR3_10270) - 1039595..1040056 (+) 462 WP_248419651.1 hypothetical protein -
  M2Y48_RS04990 (JSHR3_10280) uvrC 1040057..1041841 (+) 1785 WP_248419652.1 excinuclease ABC subunit UvrC Machinery gene
  M2Y48_RS04995 (JSHR3_10290) - 1041852..1043117 (+) 1266 WP_212877650.1 homoserine dehydrogenase -
  M2Y48_RS05000 (JSHR3_10300) - 1043118..1043462 (+) 345 WP_001211669.1 YraN family protein -
  M2Y48_RS05005 (JSHR3_10310) trxA 1043551..1043871 (+) 321 WP_000020200.1 thioredoxin -
  M2Y48_RS05010 (JSHR3_10320) trxB 1043877..1044812 (+) 936 WP_248419654.1 thioredoxin-disulfide reductase -
  M2Y48_RS05015 (JSHR3_10330) - 1044980..1045801 (+) 822 WP_248419657.1 glycosyltransferase family 25 protein -
  M2Y48_RS05020 (JSHR3_10340) - 1046007..1046255 (-) 249 WP_180432343.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68857.09 Da        Isoelectric Point: 9.6705

>NTDB_id=82458 M2Y48_RS04990 WP_248419652.1 1040057..1041841(+) (uvrC) [Helicobacter pylori strain JSHR3]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIRSYFSVRNNEITPNHRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHAFQKNSYRHYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSES
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=82458 M2Y48_RS04990 WP_248419652.1 1040057..1041841(+) (uvrC) [Helicobacter pylori strain JSHR3]
ATGGCTGATTTGTTGTCCAGTTTAAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAGAAGCTATTTTTCTGTCCGCAATAATGAAATCACGCCCA
ATCATCGCACAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAGACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAACAACTCAAACCCAAATACAATATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAATATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATAGTGGGAACAATAAGGCGGT
ATTAGTGAAGATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTTCAAAAAAACTCCTATCGGCA
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGAGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAATATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCTAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.97

100

0.97

Multiple sequence alignment