Detailed information NTG0824548

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SC043_RS09325
• Genome accession: NZ_CP138309
• Coordinates: 1866081..1868531 (-)
• Length: 816 a.a.
• NCBI ID: WP_023349248.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain B26
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1861081..1873531

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SC043_RS09295 (SC043_09295)	-	1861112..1861252 (-)	141	WP_010905476.1	hypothetical protein	-
SC043_RS09300 (SC043_09300)	-	1861840..1862607 (-)	768	WP_010905475.1	hypothetical protein	-
SC043_RS09305 (SC043_09305)	-	1862628..1862753 (-)	126	WP_021213684.1	hypothetical protein	-
SC043_RS09310 (SC043_09310)	-	1862880..1863815 (-)	936	WP_031297127.1	tyrosine-type recombinase/integrase	-
SC043_RS09315 (SC043_09315)	eno	1863903..1865204 (-)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
SC043_RS09320 (SC043_09320)	hpf	1865389..1865946 (-)	558	WP_003129564.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
SC043_RS09325 (SC043_09325)	clpC	1866081..1868531 (-)	2451	WP_023349248.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SC043_RS09330 (SC043_09330)	-	1868521..1868976 (-)	456	WP_010905471.1	CtsR family transcriptional regulator	-
SC043_RS09335 (SC043_09335)	-	1869176..1870548 (+)	1373	WP_318794322.1	IS3-like element ISLla3 family transposase	-
SC043_RS09340 (SC043_09340)	-	1870622..1871769 (+)	1148	WP_101928132.1	IS3 family transposase	-
SC043_RS09345 (SC043_09345)	greA	1871888..1872361 (-)	474	WP_025016857.1	transcription elongation factor GreA	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90467.90 Da
• Isoelectric Point: 6.5300

>NTDB_id=824548 SC043_RS09325 WP_023349248.1 1866081..1868531(-) (clpC) [Lactococcus lactis strain B26]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKMAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQTKRLDLEKELTEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLIGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=824548 SC043_RS09325 WP_023349248.1 1866081..1868531(-) (clpC) [Lactococcus lactis strain B26]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTATGCTCACCAATATCA
ATATGGCACCATTGAAAGTGCTCATTTACTGGCTGCAATGGCAACGACCTCAGGTTCAATTGCATACAGCCTCCTTGCTG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAAGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCAGAAGCCGTTGGAAC
AGAACACTTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTGAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGCAAGATGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGCTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCCCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCTTTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATCGGTGCTGGTGGCGGAATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGACGAGCCAAGTCCAGATGAAGCGATTGCTATTTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACTAGCCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCAGTGAAAATTTCTGTCAAAAATCAACAAACAAAACG
TCTTGATTTAGAAAAAGAATTAACGGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAACTTGATATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGATAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACATAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCCGGTGTTGCTGACAGCCGTCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTCGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAGTGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGTAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CACTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCGTCAGCGGTGAAATTAATTGCTGAGGTAGGTTTTGACCCAGAATATGGTGCACGTCCGC
TCCGCAAGGCTCTTCAAAAAGAAGTTGAAGACCTTTTAAGTGAACAATTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGGGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (357-453)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	99.755	100	0.998
clpC	Streptococcus thermophilus LMD-9	50.782	100	0.517
clpC	Streptococcus thermophilus LMG 18311	50.662	100	0.516
clpC	Streptococcus pneumoniae D39	48.798	100	0.498
clpC	Streptococcus pneumoniae Rx1	48.798	100	0.498
clpC	Streptococcus pneumoniae TIGR4	48.678	100	0.496
clpC	Bacillus subtilis subsp. subtilis str. 168	50.374	98.284	0.495
clpC	Streptococcus mutans UA159	48.438	100	0.494
clpE	Streptococcus mutans UA159	47.692	79.657	0.38
clpC	Lactococcus lactis subsp. cremoris KW2	46.87	80.27	0.376
clpE	Streptococcus pneumoniae TIGR4	47.687	76.838	0.366
clpE	Streptococcus pneumoniae Rx1	47.687	76.838	0.366
clpE	Streptococcus pneumoniae D39	47.687	76.838	0.366
clpE	Streptococcus pneumoniae R6	47.687	76.838	0.366