Detailed information NTG0824533

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SC043_RS05010
• Genome accession: NZ_CP138309
• Coordinates: 965833..968436 (+)
• Length: 867 a.a.
• NCBI ID: WP_003130040.1
• Uniprot ID: Q9CFF3
• Organism: Lactococcus lactis strain B26
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 960833..973436

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SC043_RS04990 (SC043_04990)	-	961034..961879 (+)	846	WP_010906020.1	oxidoreductase	-
SC043_RS04995 (SC043_04995)	purF	961994..963493 (+)	1500	WP_010906019.1	amidophosphoribosyltransferase	-
SC043_RS05000 (SC043_05000)	-	963603..964226 (+)	624	WP_003130037.1	NAD-dependent epimerase/dehydratase family protein	-
SC043_RS05005 (SC043_05005)	-	964259..965599 (-)	1341	WP_003130038.1	hypothetical protein	-
SC043_RS05010 (SC043_05010)	clpC	965833..968436 (+)	2604	WP_003130040.1	ATP-dependent chaperone ClpB	Regulator
SC043_RS05015 (SC043_05015)	purM	968619..969641 (+)	1023	WP_003130042.1	phosphoribosylformylglycinamidine cyclo-ligase	-
SC043_RS05020 (SC043_05020)	purN	969669..970217 (+)	549	WP_003130044.1	phosphoribosylglycinamide formyltransferase	-
SC043_RS05025 (SC043_05025)	-	970384..971973 (+)	1590	WP_010906017.1	ABC transporter ATP-binding protein	-
SC043_RS05030 (SC043_05030)	-	972024..972554 (-)	531	WP_003130052.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 867 a.a.
• Molecular weight: 97335.08 Da
• Isoelectric Point: 4.8188

>NTDB_id=824533 SC043_RS05010 WP_003130040.1 965833..968436(+) (clpC) [Lactococcus lactis strain B26]
MDIEKMTTTMQEALGSAQQIAQVRHHQVIEVPHLWRIFVQPNSFGANFYKDLGIDLDDYTNLIEKEIDKINSVEGSNITY
GQNLSPDLFQIFTEADKIAQKMGDEYLSTEIILLALFELKQNPLTSYLVSHGLTKAKAQAAIEKLRGGDKVTSQNAEETY
KALEKYGVDLVAQVKSGKQDPVIGRDEEIRDVIRVLSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPENLKDKTIF
SLDMGALIAGAKYRGEFEERLKAVLNEVKKSDGQIILFIDELHTIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDE
YRKYMETDKALERRFQKVLVTEPTVEDTISILRGLKERFEIHHGVTIHDNALVAAATLSNRYITDRFLPDKAIDLVDEAS
ATIRVEMNSLPTELDQANRRLMQLEIEEAALKKERDDASKKRLEIIRGEIAELREENNQLKAQWEAEKKEVGNISEKRNE
LEHARHELEEAQNEGNLEKAAALRYGKIPEIEKELKAIEEKAKSDDLSLVQESVTEEQITEVVGRMTGIPITKLVEGERE
KLLHLPETLHQRVVGQDEAVEAVSDAIIRARAGIQDPNRPLGSFLFLGPTGVGKTELAKALAENLFDSEEHMVRIDMSEY
MEKHSVSRLVGAPPGYVGYDEGGQLTEAVRRNPYTIILLDEIEKAHPDVFNILLQVLDDGRLTDSKGVLVDFKNTVLIMT
SNVGSQYLLDNVGENGEISEETTENVMSQLRAHFKPEFLNRIDDTILFKPLALEDIKNIIVKMTSQLSHRLEEMDVQLEL
SEEVKVWIAENAYEPAYGARPLKRYLTKVIENPLAKLIIGGKIPPKSKVIVTLVENKIDFDIQTIAE

Nucleotide

• Length: 2604 bp

>NTDB_id=824533 SC043_RS05010 WP_003130040.1 965833..968436(+) (clpC) [Lactococcus lactis strain B26]
ATGGACATCGAAAAAATGACAACAACGATGCAAGAAGCACTTGGTTCAGCGCAACAAATTGCGCAAGTTCGTCATCACCA
AGTGATTGAAGTTCCACATTTATGGCGAATTTTTGTTCAACCTAATAGTTTTGGGGCGAACTTTTATAAAGATTTAGGGA
TTGACCTAGATGACTATACAAATTTAATTGAAAAAGAAATTGACAAAATTAATTCAGTAGAAGGTTCAAATATTACTTAT
GGTCAAAACCTAAGTCCAGATTTGTTCCAAATATTTACTGAAGCAGACAAAATTGCGCAAAAAATGGGCGATGAATACTT
ATCAACTGAGATTATTCTCCTTGCCCTCTTTGAATTAAAACAAAATCCATTGACCAGTTATTTGGTTAGCCATGGACTAA
CAAAAGCAAAAGCGCAAGCTGCAATTGAAAAATTACGCGGAGGTGATAAAGTGACCAGTCAAAATGCAGAAGAAACATAC
AAAGCACTTGAAAAATATGGGGTAGATCTCGTTGCTCAAGTTAAATCAGGTAAACAAGATCCTGTCATTGGACGTGATGA
AGAAATTCGTGATGTCATTCGAGTGCTTTCTCGTAAAACAAAAAATAACCCCGTTCTTATTGGTGAACCTGGGGTTGGTA
AAACAGCCATTGTTGAAGGATTGGCACAAAGGATTGTCAGAAAAGACGTTCCTGAAAATCTGAAAGATAAAACAATCTTT
TCACTTGATATGGGTGCCCTGATTGCAGGAGCGAAATATCGTGGTGAATTTGAAGAACGTTTGAAAGCAGTCCTTAATGA
AGTGAAAAAATCAGATGGACAAATTATCCTCTTTATTGATGAACTTCATACGATTGTTGGTGCAGGTAAAACAGAAGGTT
CAATGGACGCTGGGAACCTTTTAAAACCAATGCTTGCACGTGGTGAACTCCATTTGATTGGGGCAACTACCTTGGATGAA
TATCGTAAATACATGGAAACAGATAAAGCACTTGAACGTCGTTTCCAAAAGGTATTGGTTACTGAACCTACTGTTGAAGA
TACAATTTCAATCTTGCGTGGTCTAAAAGAACGTTTTGAAATTCACCATGGAGTGACCATTCATGATAATGCTTTAGTCG
CAGCAGCAACCCTTTCAAATCGTTATATTACTGACCGATTTTTACCAGATAAAGCCATTGACTTGGTTGATGAAGCCAGT
GCAACAATTCGTGTAGAAATGAATTCACTCCCAACTGAACTTGACCAAGCTAATCGTCGCTTGATGCAATTAGAAATTGA
AGAAGCGGCCCTCAAAAAAGAACGAGATGATGCTTCTAAGAAACGTCTTGAAATTATACGTGGTGAAATTGCTGAACTTC
GAGAAGAAAATAATCAACTCAAAGCTCAATGGGAAGCTGAGAAAAAAGAAGTGGGCAATATTTCTGAAAAACGAAATGAA
TTAGAACATGCTCGCCACGAATTGGAAGAAGCTCAAAATGAAGGAAACTTAGAAAAAGCAGCAGCCCTTCGTTATGGTAA
AATTCCTGAAATTGAAAAAGAACTCAAAGCTATTGAAGAAAAAGCAAAATCAGATGATTTATCCTTAGTTCAAGAATCAG
TCACTGAAGAACAAATCACTGAAGTTGTTGGACGCATGACAGGTATTCCAATTACCAAATTGGTTGAAGGTGAACGTGAA
AAATTACTTCACTTGCCAGAAACACTGCATCAAAGGGTCGTTGGACAAGATGAAGCTGTTGAAGCCGTATCTGATGCCAT
TATTCGTGCGCGTGCAGGAATTCAAGACCCTAATCGTCCACTTGGCTCATTCCTCTTCCTCGGTCCAACTGGGGTAGGTA
AGACCGAACTCGCGAAAGCTTTGGCTGAAAATCTCTTTGATTCAGAAGAACATATGGTTCGGATTGACATGAGTGAATAT
ATGGAAAAACACTCAGTTTCTCGGTTAGTCGGAGCACCTCCAGGATATGTCGGTTACGATGAAGGAGGCCAATTGACTGA
AGCTGTTCGTCGTAATCCTTATACAATCATCTTGCTTGATGAAATCGAAAAAGCACATCCAGATGTCTTCAATATCTTGT
TGCAAGTTTTGGATGACGGCCGTTTGACTGACTCTAAAGGTGTTCTCGTTGACTTTAAGAACACAGTGTTGATTATGACT
TCAAATGTCGGTTCTCAATATTTGCTTGATAATGTTGGAGAAAATGGTGAAATTTCGGAAGAAACAACTGAAAACGTGAT
GTCTCAACTTCGGGCACATTTCAAACCAGAATTTCTAAATCGAATTGATGATACCATTCTTTTCAAACCATTGGCACTTG
AGGATATTAAGAATATTATCGTTAAAATGACTAGCCAACTTTCACATCGTCTTGAAGAAATGGATGTTCAACTTGAGTTG
AGTGAAGAAGTAAAAGTTTGGATTGCCGAAAATGCTTATGAACCAGCTTATGGTGCACGTCCACTCAAACGTTATTTGAC
AAAAGTCATCGAAAATCCATTAGCTAAGCTGATTATCGGAGGAAAAATTCCACCAAAATCAAAAGTTATTGTAACGCTTG
TAGAAAACAAGATTGACTTTGATATTCAAACGATTGCTGAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (599-764)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (771-851)

• AAA lid domain (AAA_lid_9) (344-444)

• ATPase family associated with various cellular activities (AAA) (AAA) (205-339)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-147)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-67)

3D structure

• AlphaFold DB: Q9CFF3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.444	100	0.46
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	40.935	100	0.414