Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   M2Y48_RS00725 Genome accession   NZ_AP023344
Coordinates   152298..153041 (+) Length   247 a.a.
NCBI ID   WP_000660524.1    Uniprot ID   A0AAI8F143
Organism   Helicobacter pylori strain JSHR3     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 147298..158041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2Y48_RS00700 (JSHR3_01450) panD 149449..149799 (+) 351 WP_154414081.1 aspartate 1-decarboxylase -
  M2Y48_RS00705 (JSHR3_01460) - 149810..150103 (+) 294 WP_000347922.1 YbaB/EbfC family nucleoid-associated protein -
  M2Y48_RS00710 (JSHR3_01470) - 150103..151098 (+) 996 WP_248420193.1 PDZ domain-containing protein -
  M2Y48_RS00715 (JSHR3_01480) comB6 151106..152161 (+) 1056 WP_248420195.1 P-type conjugative transfer protein TrbL Machinery gene
  M2Y48_RS00720 comB7 152197..152301 (+) 105 WP_248419940.1 comB7 lipoprotein Machinery gene
  M2Y48_RS00725 (JSHR3_01490) comB8 152298..153041 (+) 744 WP_000660524.1 virB8 family protein Machinery gene
  M2Y48_RS00730 (JSHR3_01500) comB9 153041..154006 (+) 966 WP_231216038.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  M2Y48_RS00735 (JSHR3_01510) comB10 153999..155135 (+) 1137 WP_001045734.1 DNA type IV secretion system protein ComB10 Machinery gene
  M2Y48_RS00740 (JSHR3_01530) - 155205..156618 (+) 1414 Protein_144 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  M2Y48_RS00745 (JSHR3_01540) gmd 156632..157777 (+) 1146 WP_248419941.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28684.91 Da        Isoelectric Point: 8.9546

>NTDB_id=82443 M2Y48_RS00725 WP_000660524.1 152298..153041(+) (comB8) [Helicobacter pylori strain JSHR3]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=82443 M2Y48_RS00725 WP_000660524.1 152298..153041(+) (comB8) [Helicobacter pylori strain JSHR3]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTAGACATGCAAAGCGTGTTTAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATTGTTTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATCAAAACGCAAAACAGCATTTAT
GCACAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCCATTGCAGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTTACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.972

Multiple sequence alignment