Detailed information NTG0823672

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: R6I11_RS13370
• Genome accession: NZ_CP137715
• Coordinates: 2889647..2892196 (-)
• Length: 849 a.a.
• NCBI ID: WP_003114516.1
• Uniprot ID: Q9I1A8
• Organism: Pseudomonas aeruginosa isolate FELIX_MS461
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2884647..2897196

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R6I11_RS13340 (R6I11_13340)	-	2884816..2885457 (-)	642	WP_003110901.1	LuxR C-terminal-related transcriptional regulator	-
R6I11_RS13345 (R6I11_13345)	-	2885734..2886129 (+)	396	WP_003089513.1	DUF4280 domain-containing protein	-
R6I11_RS13350 (R6I11_13350)	-	2886152..2886688 (-)	537	WP_003114514.1	toxin-antitoxin system YwqK family antitoxin	-
R6I11_RS13355 (R6I11_13355)	tssI	2886699..2888705 (-)	2007	WP_003114515.1	type VI secretion system tip protein VgrG	-
R6I11_RS13360 (R6I11_13360)	-	2888705..2888893 (-)	189	WP_003104930.1	hypothetical protein	-
R6I11_RS13365 (R6I11_13365)	-	2889053..2889625 (-)	573	WP_010895609.1	hypothetical protein	-
R6I11_RS13370 (R6I11_13370)	clpC	2889647..2892196 (-)	2550	WP_003114516.1	type VI secretion system ATPase TssH	Regulator
R6I11_RS13375 (R6I11_13375)	tssG	2892198..2893214 (-)	1017	WP_003114517.1	type VI secretion system baseplate subunit TssG	-
R6I11_RS13380 (R6I11_13380)	tssF	2893178..2894971 (-)	1794	WP_003114518.1	type VI secretion system baseplate subunit TssF	-
R6I11_RS13385 (R6I11_13385)	tssE	2894955..2895380 (-)	426	WP_003114519.1	type VI secretion system baseplate subunit TssE	-
R6I11_RS13390 (R6I11_13390)	-	2895393..2895890 (-)	498	WP_003089495.1	Hcp family type VI secretion system effector	-

Sequence

Protein

• Length: 849 a.a.
• Molecular weight: 92424.76 Da
• Isoelectric Point: 5.1045

>NTDB_id=823672 R6I11_RS13370 WP_003114516.1 2889647..2892196(-) (clpC) [Pseudomonas aeruginosa isolate FELIX_MS461]
MELAALIGRLNPDCRRALERAAQRCLQRTHHYVEIEHLLLELLDIDGGDFACLLPRFGLERDALVAEINLSLELFKAGNT
RTPALSAHTIGLLEDAVVHASVLGQAQIRSGLLLLALLDREERRALLLNSASSLLRIPHEALQANLLEWIQASREQPPAP
NRPAAGGDKPESAPDPLLDQYTQDLTAEARAGRIDPIVGRDGEIRQCVDILLRRRQNNPILVGAPGVGKTAVVEGLALRI
AAGEVPPSLQEVILRVLDLGLLQAGASMKGEFEQRLKGVIDAVRNSAQPIILFIDEAHTLIGAGGAEGGSDAANLLKPAL
ARGELRTLAATTWLEYKKYFEKDPALTRRFQLVQVEEPDEATAVEMLRGVAGKLELHHGVQIMDAAIVDAVKLSHRYISG
RQLPDKAISVLDTACARVALGQHDVPPPLESLRHREQALEEELQRLRREQATGLDHSARITALESESGDNRRTIRELETR
WDEEREAVRELLDIRRELLALSESADAAKPDEELDGRIDHLAAELARLAAGLEAIRQDDPLVPEQVDSRTVAAVIAGWTG
IPVGKMLADEAHAIRSLAQRMGQRVMGQEAALGAIAQRIQAYRAGLSDPAKPVGVFLLPGPTGVGKTETAYALADALYGG
ERNLISINLSEYQEAHTVSQLKGAPPGYVGYGSGGVLTEAVRRKPYSVVLLDEIEKAHPDVLEAFYNVFDKGVMEDGTGL
VVDFRNTVILATSNVGAELLLDSPAEQVATPAFDERLRKVLLQTFRPAFLARMTVVPYRPLEEATLEGIVVAKLEKLRER
YKAATGKQFDFDPAIVKAVLAKCSAAGARDIENVLMAQVTGKLAEWVLE

Nucleotide

• Length: 2550 bp

>NTDB_id=823672 R6I11_RS13370 WP_003114516.1 2889647..2892196(-) (clpC) [Pseudomonas aeruginosa isolate FELIX_MS461]
ATGGAACTCGCCGCCCTGATCGGCCGCCTCAACCCTGACTGTCGCCGCGCCCTGGAGCGCGCCGCGCAACGCTGCCTGCA
ACGCACCCATCATTACGTAGAGATCGAGCACCTGCTGCTGGAGCTGCTGGACATCGACGGCGGCGACTTCGCCTGCCTGC
TGCCGCGCTTCGGCCTGGAGCGCGACGCCCTGGTCGCCGAGATCAACCTGTCGCTGGAGCTGTTCAAGGCCGGCAATACC
CGCACTCCGGCGCTGTCCGCGCACACCATCGGCCTGCTCGAAGACGCCGTGGTCCACGCCAGCGTGCTCGGCCAGGCGCA
GATCCGTTCCGGCCTGCTGCTGCTCGCCCTGCTCGACCGCGAGGAGCGCCGCGCCCTGCTGCTGAACAGCGCGTCGTCGC
TACTGCGGATTCCCCACGAGGCCTTGCAGGCCAACCTGCTGGAGTGGATCCAGGCCTCCCGCGAACAGCCGCCCGCGCCG
AACCGCCCGGCGGCAGGCGGCGACAAGCCGGAAAGCGCCCCGGACCCGCTGCTCGACCAGTACACCCAGGACCTCACCGC
CGAAGCCCGCGCCGGGCGCATCGACCCCATAGTCGGGCGCGACGGGGAGATCCGCCAGTGCGTCGACATCCTCCTGCGCC
GGCGGCAGAACAACCCGATCCTGGTCGGCGCGCCGGGCGTCGGCAAGACCGCGGTGGTCGAGGGCCTGGCCCTGCGCATC
GCCGCCGGCGAGGTGCCGCCGTCGTTGCAGGAGGTGATCCTGCGGGTGCTCGACCTCGGCCTGTTGCAGGCCGGCGCCAG
CATGAAGGGCGAGTTCGAGCAGCGCCTCAAGGGCGTGATCGACGCCGTGCGCAACAGCGCGCAGCCGATCATCCTGTTCA
TCGACGAGGCGCACACGCTGATCGGCGCCGGCGGCGCGGAAGGCGGCAGCGACGCCGCCAACCTGCTCAAGCCGGCCCTG
GCGCGCGGCGAGTTGCGCACCCTGGCGGCCACCACCTGGCTGGAATACAAGAAATACTTCGAGAAGGACCCGGCGCTGAC
CCGGCGCTTCCAGCTGGTCCAGGTCGAGGAGCCGGACGAGGCCACCGCCGTGGAGATGCTGCGCGGCGTCGCCGGCAAGC
TGGAACTGCATCACGGCGTGCAGATCATGGACGCGGCCATCGTCGATGCGGTGAAGCTGTCGCATCGCTACATCTCCGGC
CGCCAGTTGCCGGACAAGGCGATCAGCGTGCTCGACACCGCCTGCGCGCGGGTCGCCCTCGGCCAGCACGACGTGCCGCC
GCCGCTGGAAAGCCTGCGCCATCGCGAGCAGGCGCTGGAAGAGGAATTGCAGCGGCTGCGCCGGGAACAGGCCACCGGCC
TCGACCACAGCGCGCGTATCACCGCCCTGGAAAGCGAGTCGGGCGATAACCGCCGGACCATCCGCGAGCTGGAGACCCGC
TGGGACGAGGAACGCGAAGCGGTGCGCGAACTGCTCGACATCCGCCGCGAACTGCTGGCCCTCAGCGAAAGCGCCGACGC
GGCCAAGCCCGACGAGGAACTGGACGGTCGCATCGACCACCTGGCCGCCGAACTGGCGCGCCTGGCGGCCGGCCTCGAAG
CCATCCGCCAGGACGACCCGCTGGTTCCCGAGCAGGTGGACTCGCGTACCGTGGCCGCGGTGATCGCCGGCTGGACCGGC
ATCCCGGTGGGCAAGATGCTCGCCGACGAAGCCCACGCCATCCGTTCCCTGGCGCAACGAATGGGCCAGCGGGTGATGGG
CCAGGAGGCCGCCCTGGGCGCCATCGCCCAGCGCATCCAGGCCTATCGCGCCGGACTCAGCGACCCGGCCAAGCCGGTCG
GCGTATTCCTCCTGCCCGGCCCCACCGGCGTGGGCAAGACCGAGACCGCCTACGCCCTGGCCGACGCCCTCTACGGCGGC
GAACGCAACCTGATCAGCATCAACCTCTCCGAGTACCAGGAGGCCCACACCGTCAGCCAGCTCAAGGGCGCCCCGCCCGG
CTACGTCGGCTACGGCAGCGGCGGCGTGCTCACCGAAGCGGTGCGCCGCAAGCCCTATTCGGTGGTGCTGCTGGACGAGA
TCGAGAAAGCCCATCCGGACGTGCTGGAAGCCTTCTACAACGTGTTCGACAAGGGCGTGATGGAAGACGGCACCGGCCTG
GTGGTGGACTTCAGGAACACCGTGATCCTCGCCACCAGCAACGTCGGCGCCGAACTGCTGCTGGACAGCCCGGCCGAACA
GGTCGCCACCCCGGCCTTCGACGAGCGCCTGCGCAAAGTCCTGCTGCAAACCTTCCGCCCGGCGTTCCTCGCGCGCATGA
CCGTGGTGCCTTACCGGCCGCTGGAGGAAGCCACCCTGGAAGGCATCGTCGTGGCCAAGCTGGAAAAACTGCGGGAACGC
TACAAGGCCGCTACCGGCAAACAGTTCGACTTCGACCCAGCCATCGTCAAGGCCGTGCTCGCCAAGTGCAGCGCGGCGGG
CGCGCGGGATATCGAGAACGTGCTGATGGCGCAGGTGACGGGGAAGTTGGCGGAGTGGGTGTTGGAGTAG

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (781-848)

• AAA lid domain (AAA_lid_9) (360-453)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (21-71)

• AAA domain (Cdc48 subfamily) (AAA_2) (611-775)

• ATPase family associated with various cellular activities (AAA) (AAA) (220-332)

3D structure

• AlphaFold DB: Q9I1A8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	37.05	100	0.376