Detailed information NTG0823562

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QHG39_RS05030
• Genome accession: NZ_CP123983
• Coordinates: 1000966..1002012 (+)
• Length: 348 a.a.
• NCBI ID: WP_011275375.1
• Uniprot ID: A0A2A1K920
• Organism: Staphylococcus haemolyticus strain SH9361
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 995966..1007012

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QHG39_RS05005 (QHG39_05005)	map	996826..997578 (+)	753	WP_011275369.1	type I methionyl aminopeptidase	-
QHG39_RS05010 (QHG39_05010)	-	997703..998560 (-)	858	WP_011275370.1	SDR family oxidoreductase	-
QHG39_RS05015 (QHG39_05015)	-	998632..999644 (-)	1013	Protein_987	HoxN/HupN/NixA family nickel/cobalt transporter	-
QHG39_RS05020 (QHG39_05020)	-	999857..1000243 (+)	387	WP_011275373.1	hypothetical protein	-
QHG39_RS05025 (QHG39_05025)	liaF	1000268..1000969 (+)	702	WP_011275374.1	cell wall-active antibiotics response protein LiaF	-
QHG39_RS05030 (QHG39_05030)	vraS	1000966..1002012 (+)	1047	WP_011275375.1	sensor histidine kinase	Regulator
QHG39_RS05035 (QHG39_05035)	vraR	1002002..1002631 (+)	630	WP_011275376.1	two-component system response regulator VraR	Regulator
QHG39_RS05040 (QHG39_05040)	-	1002695..1003906 (-)	1212	WP_011275377.1	YihY/virulence factor BrkB family protein	-
QHG39_RS05045 (QHG39_05045)	-	1004103..1004387 (-)	285	WP_011275378.1	YtxH domain-containing protein	-
QHG39_RS05050 (QHG39_05050)	-	1004393..1004857 (-)	465	WP_049394644.1	low molecular weight protein-tyrosine-phosphatase	-
QHG39_RS05055 (QHG39_05055)	-	1004999..1005208 (+)	210	WP_011275380.1	DUF1128 domain-containing protein	-
QHG39_RS05060 (QHG39_05060)	-	1005222..1006469 (+)	1248	WP_011275381.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40179.58 Da
• Isoelectric Point: 6.0550

>NTDB_id=823562 QHG39_RS05030 WP_011275375.1 1000966..1002012(+) (vraS) [Staphylococcus haemolyticus strain SH9361]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAYKINQQNQWIKS
QIEHAIEGETVGINDQNIELYNETIDLYQTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIENERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMVQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIHDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNREDDNNDD

Nucleotide

• Length: 1047 bp

>NTDB_id=823562 QHG39_RS05030 WP_011275375.1 1000966..1002012(+) (vraS) [Staphylococcus haemolyticus strain SH9361]
ATGAACCACTACTTAAGAGCTATCGGTTCAATGCTTATACTAGTTTATAGCATGTTAACCGCGTTCTTATTTATAGATAA
AGTATTTGTTAATATTATCTATTTCCAAGGTATGTTTTATACTCAAATTTTTGGGATACCTGTTTTTCTATTTTTAAATT
TAGTCATCATTTTACTTTGTATTATAGTAGGTTCAATTCTCGCATATAAAATTAATCAACAAAATCAGTGGATTAAGTCG
CAAATTGAGCATGCCATTGAAGGAGAAACAGTAGGTATCAATGATCAAAACATTGAGCTCTATAACGAAACCATAGATCT
TTATCAAACATTAGTTCCTCTAAATCAAGAGTTGCACCGTTTACGAATGAAAACGCAAAACTTAACTAATGAAAATTACA
ATATGAATGATGTCAAAGTTAAGAAAATCATTGAGAATGAACGACAGAGATTAGCTCGCGAGTTACATGACTCTGTAAGT
CAACAACTTTTTGCAGCAAGTATGATGTTATCTGCTATAAAAGAAACAAAATTAGAGGCACCGCTTGATCAACAAATACC
AGTTTTAGAGAAAATGGTTCAGGAATCTCAACTTGAAATGCGCGCATTATTACTTCATTTGAGACCTTTAGGACTAAAAG
ATAAATCACTAGGTGAAGGTATCAAAGATTTAGTTATTGATTTGCAAAAGAAAGTGCCTATGAAAGTCATACACGATATT
CAAGATTTCAAGGTTCCTAAAGGTATAGAAGATCATTTATTTAGAATTACACAAGAGGCTATATCAAATACGTTAAGACA
TTCTAATGGAACTAAAGTCACAGTGGAATTATTTAACCAACAAGATTATCTATTACTTCGAATTCAAGATAATGGTAAGG
GATTCAATGTTGACGAGAAATTAGAACAAAGTTATGGATTAAAAAATATGAGAGAACGCGCATTAGAAATTGGTGCGACA
TTCCATATTGTTTCGTTACCGGATTCTGGAACGAGAATAGAAGTTAAAGCACCATTAAATAGGGAGGATGATAATAATGA
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A2A1K920

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.643	99.713	0.914