Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NUG19_RS13475 Genome accession   NZ_CP123853
Coordinates   2733266..2733982 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain FDA209P     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2728266..2738982
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NUG19_RS13455 - 2729358..2730308 (+) 951 WP_000790324.1 LacI family DNA-binding transcriptional regulator -
  NUG19_RS13460 - 2730457..2731941 (+) 1485 WP_042727666.1 sucrose-6-phosphate hydrolase -
  NUG19_RS13465 - 2731938..2732897 (+) 960 WP_001253302.1 carbohydrate kinase -
  NUG19_RS13470 - 2733085..2733194 (-) 110 Protein_2611 hypothetical protein -
  NUG19_RS13475 agrA 2733266..2733982 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  NUG19_RS13480 agrC 2734001..2735297 (-) 1297 Protein_2613 quorum-sensing sensor histidine kinase AgrC -
  NUG19_RS13485 agrD 2735322..2735462 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  NUG19_RS13490 agrB 2735459..2736028 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  NUG19_RS13495 - 2736264..2736398 (+) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  NUG19_RS13500 - 2736994..2737779 (-) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  NUG19_RS13505 - 2738140..2738766 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=822818 NUG19_RS13475 WP_000688498.1 2733266..2733982(-) (agrA) [Staphylococcus aureus strain FDA209P]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=822818 NUG19_RS13475 WP_000688498.1 2733266..2733982(-) (agrA) [Staphylococcus aureus strain FDA209P]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996