Detailed information NTG0822778

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NUG19_RS00455
• Genome accession: NZ_CP123853
• Coordinates: 83540..84583 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDA209P
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 78540..89583

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NUG19_RS00425	-	78963..79073 (+)	111	WP_001790257.1	hypothetical protein	-
NUG19_RS00430	-	79102..79515 (+)	414	WP_001549145.1	hypothetical protein	-
NUG19_RS00435	-	80005..80991 (-)	987	WP_042727578.1	aromatic acid exporter family protein	-
NUG19_RS00440	map	81466..82224 (+)	759	WP_000636144.1	type I methionyl aminopeptidase	-
NUG19_RS00445	-	82441..82827 (+)	387	WP_001110179.1	hypothetical protein	-
NUG19_RS00450	liaF	82842..83543 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
NUG19_RS00455	vraS	83540..84583 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NUG19_RS00460	vraR	84573..85202 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
NUG19_RS00465	-	85314..86531 (-)	1218	WP_042727579.1	YihY/virulence factor BrkB family protein	-
NUG19_RS00470	-	86809..87084 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
NUG19_RS00475	-	87091..87555 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
NUG19_RS00480	-	87702..87902 (+)	201	WP_000180463.1	DUF1128 family protein	-
NUG19_RS00485	-	87905..89161 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=822778 NUG19_RS00455 WP_001017131.1 83540..84583(+) (vraS) [Staphylococcus aureus strain FDA209P]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=822778 NUG19_RS00455 WP_001017131.1 83540..84583(+) (vraS) [Staphylococcus aureus strain FDA209P]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1