Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   R8586_RS00850 Genome accession   NZ_AP026922
Coordinates   158807..159247 (-) Length   146 a.a.
NCBI ID   WP_000861968.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700038     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 153807..164247
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8586_RS00825 (PC0038_01550) - 154160..154693 (+) 534 WP_000729036.1 hypothetical protein -
  R8586_RS00830 (PC0038_01560) nrdI 154771..155241 (+) 471 WP_000692018.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  R8586_RS00835 (PC0038_01570) - 155534..156796 (-) 1263 WP_000075791.1 NRAMP family divalent metal transporter -
  R8586_RS00840 (PC0038_01580) - 156939..157892 (-) 954 WP_001155321.1 IS30-like element ISSpn8 family transposase -
  R8586_RS00845 (PC0038_01590) - 158352..158810 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  R8586_RS00850 (PC0038_01600) brsR 158807..159247 (-) 441 WP_000861968.1 LytTR family DNA-binding domain-containing protein Regulator
  R8586_RS00855 - 159335..159460 (-) 126 WP_001822433.1 hypothetical protein -
  R8586_RS00860 (PC0038_01610) - 159831..160697 (+) 867 WP_000537006.1 helix-turn-helix domain-containing protein -
  R8586_RS00865 (PC0038_01620) - 160850..160978 (+) 129 WP_001257108.1 hypothetical protein -
  R8586_RS00870 (PC0038_01630) - 161034..161591 (+) 558 WP_000358739.1 phosphopantothenate--cysteine ligase family flavoprotein -
  R8586_RS00875 (PC0038_01640) - 161812..162918 (+) 1107 WP_000608717.1 pyridoxal-dependent decarboxylase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17137.81 Da        Isoelectric Point: 5.9797

>NTDB_id=82272 R8586_RS00850 WP_000861968.1 158807..159247(-) (brsR) [Streptococcus pneumoniae strain PZ900700038]
MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=82272 R8586_RS00850 WP_000861968.1 158807..159247(-) (brsR) [Streptococcus pneumoniae strain PZ900700038]
ATGAAAGTAGAATTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAGCCGACAGATAAAGT
TCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGGAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363

Multiple sequence alignment