Detailed information NTG0822472

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: R6U47_RS22180
• Genome accession: NZ_CP137561
• Coordinates: 4689739..4692537 (-)
• Length: 932 a.a.
• NCBI ID: WP_324001172.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa strain CPA0053
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4684739..4697537

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R6U47_RS22155 (R6U47_22160)	creC	4685124..4686548 (-)	1425	WP_324001170.1	two-component system sensor histidine kinase CreC	-
R6U47_RS22160 (R6U47_22165)	creB	4686548..4687237 (-)	690	WP_003084734.1	two-component system response regulator CreB	-
R6U47_RS22165 (R6U47_22170)	-	4687322..4687831 (-)	510	WP_003113269.1	ATP-dependent zinc protease	-
R6U47_RS22170 (R6U47_22175)	-	4687974..4688861 (+)	888	WP_003099939.1	acyltransferase	-
R6U47_RS22175 (R6U47_22180)	-	4689059..4689637 (-)	579	WP_003084725.1	DUF2780 domain-containing protein	-
R6U47_RS22180 (R6U47_22185)	clpC	4689739..4692537 (-)	2799	WP_324001172.1	AAA family protein disaggregase ClpG	Regulator
R6U47_RS22185 (R6U47_22190)	mdtD	4692911..4694344 (+)	1434	WP_003084717.1	multidrug transporter subunit MdtD	-
R6U47_RS22190 (R6U47_22195)	-	4694346..4694720 (+)	375	WP_023086915.1	DUF1232 domain-containing protein	-
R6U47_RS22195 (R6U47_22200)	-	4694714..4695238 (-)	525	WP_003099931.1	ATP-dependent zinc protease	-
R6U47_RS22200 (R6U47_22205)	-	4695389..4695598 (-)	210	WP_003084710.1	cold-shock protein	-
R6U47_RS22205 (R6U47_22210)	dbpA	4695946..4697322 (+)	1377	WP_003113273.1	ATP-dependent RNA helicase DbpA	-

Sequence

Protein

• Length: 932 a.a.
• Molecular weight: 103337.88 Da
• Isoelectric Point: 6.9855

>NTDB_id=822472 R6U47_RS22180 WP_324001172.1 4689739..4692537(-) (clpC) [Pseudomonas aeruginosa strain CPA0053]
MAQELCAICHERPAVARVSLVQNGQRRELALCELHYRQLMRQQRMRSPLESLFGGGSPFDEIFSGFGEQSPVTPVRAREP
EAVDIAEYFSKQTTEYLQRAAQVAAEFGKREVDTEHLLYALADADVVQAVLKQFGLSPADLKQYIEANAVRGASKGEASE
DMTISPRVKSALQHAFALSRELGHSYVGPEHLLLGLAAVPDSFAGTLLKKYGLTEQALRQKAVKVVGKGAEDGRVDGPSN
TPQLDKFSRDLTRLAREGKLDPVIGRSKEVETTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRMVQGEVPEVLRDKRL
VELNINAMVAGAKYRGEFEERLKQVMDELQAAQSEIILFIDEVHTIVGAGQGGGEGGLDVANVLKPAMARGEMNLIGATT
LNEYQKYIEKDAALERRFQPVFVPEPTVEQTISILRGLRDKLEGHHKVTIRDEAFVAAAELSDRYIGNRFLPDKAIDLID
QAAARVRIASTSRPAEIQELEAELAQLKREQDYAASRKWYDEAKVFEKRIQERKEHLEQITERWQQTQGSKTEEVRVEDI
AEIISRLTGIPVTELTAEEREKLLQMEERLHQRVIGQQEAITAVSDAVRLARAGLRQGSRPIATFLFLGPTGVGKTELAK
ALAGVVFGDEDAMIRIDMSEYMERHAVSRLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHADVNNILLQVFDD
GRLTDGKGRVVDFTNTIIIATSNLGSELIMKNAQAGEFAQPPEKLKRELMTTLRGHFRPEFLNRLDEVIVFESLSKAQIE
DIVRLQLERVKRAAHAQDIYLHIDDSLVGHLAEEAYQPEFGARELKRQIRQQLETRLATAMLKGEVKEGETVTFFYDAKD
GVGYRKGAAPKPAARKKSGAGETPKGRATAARKPAAKKGAAAKGKADKPKAK

Nucleotide

• Length: 2799 bp

>NTDB_id=822472 R6U47_RS22180 WP_324001172.1 4689739..4692537(-) (clpC) [Pseudomonas aeruginosa strain CPA0053]
ATGGCCCAGGAACTTTGCGCTATCTGCCACGAACGTCCCGCCGTCGCCCGCGTCAGCCTGGTACAGAACGGCCAGCGCCG
CGAACTCGCCCTCTGCGAACTGCACTACCGCCAGTTGATGCGCCAGCAGCGCATGCGCTCGCCGCTGGAGTCGCTGTTCG
GCGGCGGCAGCCCGTTCGACGAGATCTTCTCCGGCTTCGGCGAGCAGAGCCCGGTCACCCCGGTGCGCGCCCGCGAGCCG
GAGGCGGTGGACATCGCCGAGTACTTCAGCAAGCAGACCACCGAGTACCTGCAACGCGCCGCGCAGGTCGCCGCCGAATT
CGGCAAGCGCGAAGTGGACACCGAGCACCTGCTCTACGCCCTGGCCGACGCCGACGTGGTGCAGGCGGTGCTCAAGCAGT
TCGGCCTGTCGCCGGCCGACCTCAAGCAGTACATCGAGGCCAACGCCGTGCGCGGCGCCAGCAAGGGCGAGGCGAGCGAG
GACATGACCATCTCGCCGCGGGTGAAGAGCGCCTTGCAGCATGCCTTCGCCCTGTCCCGCGAACTCGGCCACAGCTATGT
CGGCCCCGAGCACCTGTTGCTCGGCCTGGCGGCGGTGCCGGACAGCTTCGCCGGGACGCTCCTGAAGAAGTACGGCCTGA
CCGAGCAGGCGCTACGGCAGAAAGCGGTCAAGGTGGTCGGCAAGGGCGCCGAGGACGGCCGCGTGGACGGCCCGAGCAAC
ACTCCGCAACTGGACAAGTTCAGCCGCGACCTGACCCGGCTGGCCCGCGAAGGCAAGCTCGATCCGGTGATCGGCCGCTC
GAAGGAAGTCGAGACCACCATCGAGGTTCTCGCCCGGCGCAAGAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCG
GCAAGACCGCCATCGTCGAAGGCCTGGCCCAGCGCATGGTCCAGGGCGAGGTGCCGGAGGTGCTGCGCGACAAGCGCCTG
GTCGAACTGAACATCAACGCCATGGTCGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAACGCCTCAAGCAGGTGATGGA
CGAACTGCAGGCGGCGCAGAGCGAGATCATCCTGTTCATCGACGAGGTGCACACCATCGTCGGTGCCGGCCAGGGCGGCG
GCGAAGGCGGGCTGGACGTGGCCAACGTGCTGAAGCCGGCGATGGCGCGTGGCGAGATGAACCTGATCGGCGCCACCACC
CTCAACGAGTACCAGAAGTACATCGAGAAGGACGCCGCGCTGGAGCGGCGCTTCCAGCCGGTGTTCGTCCCCGAGCCGAC
GGTGGAGCAGACCATCTCCATCCTCCGTGGCCTGCGCGACAAGCTCGAAGGCCACCACAAGGTGACCATCCGCGACGAGG
CCTTCGTCGCCGCCGCCGAGCTGTCCGATCGCTACATCGGCAACCGCTTCCTGCCGGACAAGGCCATCGACCTGATCGAC
CAGGCCGCCGCCCGCGTGCGCATCGCCAGCACCTCGCGGCCGGCCGAGATCCAGGAACTGGAGGCCGAGCTGGCGCAGCT
CAAGCGCGAGCAGGACTACGCCGCCAGCCGCAAGTGGTACGACGAGGCGAAGGTCTTCGAGAAACGCATCCAGGAACGCA
AGGAACACCTCGAGCAGATCACCGAGCGCTGGCAGCAGACCCAGGGGTCGAAGACCGAGGAGGTGCGGGTCGAGGACATC
GCCGAGATCATCTCCAGGCTCACCGGCATCCCGGTCACCGAACTGACCGCCGAGGAGCGCGAGAAGCTCCTGCAGATGGA
AGAGCGCCTGCACCAGCGGGTGATCGGCCAGCAGGAAGCGATCACCGCGGTCAGCGACGCCGTGCGCCTGGCCCGCGCCG
GGCTGCGCCAGGGCAGCCGGCCGATCGCCACCTTCCTGTTCCTCGGCCCGACCGGGGTGGGCAAGACCGAGCTGGCCAAG
GCCCTGGCCGGGGTGGTGTTCGGCGACGAAGACGCGATGATCCGCATCGACATGAGCGAATACATGGAGCGCCACGCGGT
GTCCCGGCTGATCGGTGCGCCGCCGGGCTACGTCGGCTACGACGAGGGCGGCCAGCTCACCGAGCGGGTGCGCCGGCGGC
CGTACAGCGTGATCCTGCTCGATGAGATCGAGAAGGCCCACGCCGACGTCAACAACATCCTCCTGCAGGTGTTCGACGAC
GGCCGCCTGACCGACGGCAAGGGGCGCGTGGTGGACTTCACCAATACCATCATCATCGCCACCAGCAACCTCGGCTCCGA
GCTGATCATGAAGAACGCCCAGGCCGGCGAGTTCGCCCAGCCGCCGGAGAAGCTCAAGCGCGAACTGATGACTACCCTGC
GCGGACATTTCCGCCCGGAATTCCTCAACCGCCTCGACGAGGTGATCGTCTTCGAGTCGCTGAGCAAGGCGCAGATCGAG
GACATCGTGCGCCTGCAACTGGAGCGGGTGAAGCGCGCCGCGCACGCTCAGGACATCTACCTGCACATCGACGACAGCCT
GGTCGGCCACCTCGCCGAAGAGGCCTACCAGCCGGAGTTCGGCGCCCGCGAGCTGAAGCGGCAGATCCGCCAGCAACTGG
AGACGCGCCTGGCCACGGCGATGCTCAAGGGCGAGGTGAAAGAGGGCGAGACGGTCACCTTCTTCTACGACGCCAAGGAC
GGCGTCGGCTACCGCAAGGGCGCCGCGCCGAAGCCGGCGGCACGCAAGAAATCCGGCGCCGGCGAGACGCCCAAGGGCCG
CGCGACGGCGGCGAGGAAGCCGGCGGCGAAGAAAGGCGCCGCCGCCAAGGGCAAGGCCGACAAGCCGAAGGCCAAGTGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (286-419)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (794-873)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (100-147)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (175-226)

• AAA domain (Cdc48 subfamily) (AAA_2) (620-788)

• AAA lid domain (AAA_lid_9) (427-524)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	50.249	86.052	0.432
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.113	85.622	0.386
clpC	Streptococcus thermophilus LMD-9	42.684	88.734	0.379
clpC	Streptococcus thermophilus LMG 18311	42.443	88.734	0.377
clpC	Streptococcus mutans UA159	41.262	88.412	0.365