Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R2B38_RS41030 Genome accession   NZ_CP137549
Coordinates   9250387..9251049 (-) Length   220 a.a.
NCBI ID   WP_318020874.1    Uniprot ID   -
Organism   Streptomyces sp. N50     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 9245387..9256049
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2B38_RS41010 (R2B38_41010) - 9246715..9247722 (+) 1008 WP_318020870.1 ABC transporter substrate-binding protein -
  R2B38_RS41015 (R2B38_41015) - 9247722..9248567 (+) 846 WP_318020871.1 ABC transporter ATP-binding protein -
  R2B38_RS41020 (R2B38_41020) - 9248564..9249385 (+) 822 WP_318020872.1 ABC transporter permease -
  R2B38_RS41025 (R2B38_41025) - 9249382..9250335 (+) 954 WP_318020873.1 zinc-binding alcohol dehydrogenase family protein -
  R2B38_RS41030 (R2B38_41030) vraR 9250387..9251049 (-) 663 WP_318020874.1 response regulator transcription factor Regulator
  R2B38_RS41035 (R2B38_41035) - 9251046..9252215 (-) 1170 WP_318020875.1 sensor histidine kinase -
  R2B38_RS41040 (R2B38_41040) - 9252354..9253148 (+) 795 WP_318020876.1 hypothetical protein -
  R2B38_RS41045 (R2B38_41045) - 9253302..9253541 (+) 240 WP_318020877.1 hypothetical protein -
  R2B38_RS41050 (R2B38_41050) - 9253538..9254245 (+) 708 WP_318020878.1 sigma-70 family RNA polymerase sigma factor -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24255.17 Da        Isoelectric Point: 6.3440

>NTDB_id=822305 R2B38_RS41030 WP_318020874.1 9250387..9251049(-) (vraR) [Streptomyces sp. N50]
MTISVLLADDQALVRMAFRSLLDTMPDITVLGEAADGQEAVDLTRRTLPDVVLMDVRMPVMDGIEATRRITAATASRVLI
LTTFDLDEYAFEGLRAGACGFLLKDVVPTVLRAAIRSVASGDAVLTPRITRGLVDRFAQIAPWPHADDAGALFARLTPRE
KDVFHLIAAGLSNAEIAERLFLTEATVKTHITRILTKLRLRDRVQVVIFAYEHQLRPHGE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=822305 R2B38_RS41030 WP_318020874.1 9250387..9251049(-) (vraR) [Streptomyces sp. N50]
ATGACGATCTCGGTCCTCCTCGCCGACGACCAGGCACTCGTCCGCATGGCCTTCCGCAGCCTCCTCGACACGATGCCGGA
CATCACCGTCCTCGGCGAAGCCGCCGACGGGCAGGAGGCCGTCGACCTCACGCGGCGCACGCTGCCGGACGTGGTGCTCA
TGGACGTACGCATGCCGGTCATGGACGGCATCGAGGCAACCCGGCGCATCACCGCCGCGACAGCCTCCCGCGTCCTGATC
CTCACCACCTTCGACCTCGACGAGTACGCCTTCGAGGGCCTCCGCGCGGGAGCCTGCGGATTCCTCCTCAAGGACGTCGT
CCCGACCGTGCTGCGGGCGGCGATCCGGTCCGTGGCCTCCGGCGACGCCGTCCTCACCCCGCGCATCACCCGAGGTCTCG
TCGACCGCTTCGCCCAGATCGCCCCGTGGCCCCACGCGGACGACGCCGGTGCCCTCTTCGCCCGACTGACACCCCGCGAG
AAGGACGTGTTCCACCTCATCGCCGCCGGCCTGTCGAACGCCGAGATCGCGGAGCGCCTCTTCCTCACCGAGGCCACGGT
CAAGACCCACATCACCCGCATCCTCACCAAACTGCGGCTCCGCGACCGTGTGCAGGTCGTGATCTTCGCCTACGAACATC
AGCTGCGCCCGCACGGCGAGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(156-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.889

98.182

0.382