Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R2B38_RS31630 Genome accession   NZ_CP137549
Coordinates   7010885..7011571 (+) Length   228 a.a.
NCBI ID   WP_318019255.1    Uniprot ID   -
Organism   Streptomyces sp. N50     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7005885..7016571
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2B38_RS31610 (R2B38_31610) - 7005959..7006192 (-) 234 WP_019061015.1 hypothetical protein -
  R2B38_RS31615 (R2B38_31615) - 7006636..7008756 (+) 2121 WP_318019252.1 DNA topoisomerase IV subunit B -
  R2B38_RS31620 (R2B38_31620) - 7009216..7009740 (+) 525 WP_318019253.1 CcdC protein domain-containing protein -
  R2B38_RS31625 (R2B38_31625) - 7009737..7010888 (+) 1152 WP_318019254.1 sensor histidine kinase -
  R2B38_RS31630 (R2B38_31630) vraR 7010885..7011571 (+) 687 WP_318019255.1 response regulator transcription factor Regulator
  R2B38_RS31635 (R2B38_31635) - 7011641..7012201 (+) 561 WP_318019256.1 DUF485 domain-containing protein -
  R2B38_RS31640 (R2B38_31640) - 7012198..7013790 (+) 1593 WP_318019257.1 cation acetate symporter -
  R2B38_RS31645 (R2B38_31645) - 7013839..7014531 (-) 693 WP_318019258.1 response regulator -
  R2B38_RS31650 (R2B38_31650) - 7014691..7015506 (+) 816 WP_033283983.1 ABC transporter ATP-binding protein -
  R2B38_RS31655 (R2B38_31655) - 7015496..7016374 (+) 879 WP_318019259.1 ABC transporter permease -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24274.73 Da        Isoelectric Point: 4.8752

>NTDB_id=822290 R2B38_RS31630 WP_318019255.1 7010885..7011571(+) (vraR) [Streptomyces sp. N50]
MTDEAVRKPARVVVADDQTVVREGIVMLLGLLPGIEVVGAAADGDEAVRLVAELAPDVVLMDLRMPRCDGVEATRRIRAE
HPGTQVVVLTTFADDASLFPALRAGARGYLTKDAGGDEIVRAVESVLSGDAGLSPSIQRRLLERLSEPEPQPASESAEPP
DGLTARETEVLLLIAEGLTNQEIARTLHVSTATVKTHINNLFAKTGLKDRAQAVRYAYGKGLVRPPAS

Nucleotide


Download         Length: 687 bp        

>NTDB_id=822290 R2B38_RS31630 WP_318019255.1 7010885..7011571(+) (vraR) [Streptomyces sp. N50]
ATGACGGATGAGGCCGTGAGGAAACCCGCGCGGGTCGTGGTCGCGGACGACCAGACCGTCGTACGGGAAGGCATCGTGAT
GCTGCTGGGGCTGCTGCCCGGGATCGAGGTCGTCGGCGCCGCCGCCGACGGGGACGAGGCGGTGCGGCTCGTGGCCGAAC
TCGCCCCGGACGTCGTCCTGATGGACCTGCGCATGCCGCGCTGCGACGGTGTCGAGGCAACCCGGCGGATCCGCGCCGAG
CACCCGGGGACGCAGGTCGTGGTGCTCACGACGTTCGCGGACGACGCCTCGCTGTTCCCGGCGCTGCGCGCGGGGGCGCG
TGGCTATCTCACCAAGGACGCGGGCGGCGACGAGATCGTACGGGCCGTGGAGAGCGTGCTGTCGGGGGACGCGGGGCTGT
CGCCGAGCATCCAACGCCGGTTGCTGGAGCGCCTGTCGGAGCCCGAGCCGCAGCCGGCGTCGGAGTCGGCCGAGCCGCCG
GACGGGCTCACCGCGCGGGAGACGGAGGTGCTGCTGCTGATCGCCGAGGGCCTGACGAATCAGGAGATCGCCCGCACACT
GCATGTCTCCACGGCGACGGTGAAGACCCACATCAACAACCTGTTCGCCAAGACGGGGCTCAAGGACCGTGCGCAGGCGG
TGCGTTACGCCTACGGGAAAGGACTGGTGCGGCCACCAGCGAGTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(12-123)

Bacterial regulatory proteins, luxR family (GerE)

(162-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.72

93.86

0.373