Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R2B38_RS29565 Genome accession   NZ_CP137549
Coordinates   6531387..6532052 (-) Length   221 a.a.
NCBI ID   WP_318018950.1    Uniprot ID   -
Organism   Streptomyces sp. N50     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6526387..6537052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2B38_RS29550 (R2B38_29550) - 6527558..6528439 (-) 882 WP_318018947.1 alpha/beta hydrolase -
  R2B38_RS29555 (R2B38_29555) - 6528624..6529208 (+) 585 WP_318018948.1 TetR/AcrR family transcriptional regulator -
  R2B38_RS29560 (R2B38_29560) - 6529261..6531285 (-) 2025 WP_318018949.1 prolyl oligopeptidase family serine peptidase -
  R2B38_RS29565 (R2B38_29565) vraR 6531387..6532052 (-) 666 WP_318018950.1 response regulator transcription factor Regulator
  R2B38_RS29570 (R2B38_29570) - 6532049..6533242 (-) 1194 WP_318018951.1 sensor histidine kinase -
  R2B38_RS29575 (R2B38_29575) - 6533394..6533612 (+) 219 WP_318018952.1 hypothetical protein -
  R2B38_RS29580 (R2B38_29580) - 6533605..6534519 (+) 915 WP_318018953.1 ABC transporter ATP-binding protein -
  R2B38_RS29585 (R2B38_29585) - 6534516..6535529 (+) 1014 WP_318018954.1 ABC transporter permease -
  R2B38_RS29590 (R2B38_29590) - 6535578..6536945 (-) 1368 WP_033282778.1 L-serine ammonia-lyase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23540.25 Da        Isoelectric Point: 6.2414

>NTDB_id=822282 R2B38_RS29565 WP_318018950.1 6531387..6532052(-) (vraR) [Streptomyces sp. N50]
MIRVLLVDDDPLVRSGLRLMLSGADDIEVVAEAADGGEVPALVDEHAPDLVLMDIRMPGVDGLKATELLRARPGAPAVVM
LTTFKDDEQVLGALRAGAAGFLLKHTPPAEIVAAVRRVKAGEPVLSPAVTEQLIARVTRGGDGTVPRRPEAAEARVRLDR
LGDREREVAVAVGRGRTNAEIAAELYMSVATVKAHVSHILTKLEHTNRVQIALTVHYAGLV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=822282 R2B38_RS29565 WP_318018950.1 6531387..6532052(-) (vraR) [Streptomyces sp. N50]
ATGATCCGTGTGCTGCTCGTCGACGACGACCCGCTGGTCCGCTCGGGACTCCGGCTGATGCTCAGCGGCGCCGACGACAT
CGAGGTCGTGGCCGAGGCGGCGGACGGCGGCGAGGTGCCCGCCCTGGTCGACGAGCACGCCCCCGACCTGGTGCTGATGG
ACATCCGGATGCCCGGCGTGGACGGCCTGAAGGCTACCGAACTGCTGCGGGCCCGGCCCGGCGCACCGGCCGTCGTGATG
CTGACGACCTTCAAGGACGACGAGCAGGTCCTCGGCGCGCTGCGCGCGGGCGCGGCCGGTTTCCTGCTCAAGCACACCCC
GCCCGCCGAGATCGTCGCGGCGGTACGCCGGGTGAAGGCGGGCGAGCCGGTGCTCTCCCCCGCCGTGACCGAGCAGCTCA
TCGCCCGGGTCACCCGGGGCGGCGACGGTACGGTCCCGCGCCGCCCGGAGGCCGCCGAGGCCCGCGTCCGCCTCGACCGG
CTGGGCGACCGGGAACGCGAGGTCGCCGTGGCCGTCGGCCGGGGCAGGACCAACGCGGAGATCGCGGCCGAGCTGTACAT
GAGCGTGGCCACCGTCAAGGCGCACGTCTCCCACATCCTCACCAAGCTGGAACACACCAACCGGGTCCAGATCGCCCTGA
CCGTGCACTACGCCGGCCTGGTCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(161-213)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.727

99.548

0.376