Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R2B38_RS27590 Genome accession   NZ_CP137549
Coordinates   6096177..6096791 (+) Length   204 a.a.
NCBI ID   WP_318018665.1    Uniprot ID   -
Organism   Streptomyces sp. N50     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6091177..6101791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2B38_RS27575 (R2B38_27575) - 6093282..6094232 (+) 951 WP_318018663.1 ABC transporter ATP-binding protein -
  R2B38_RS27580 (R2B38_27580) - 6094229..6094969 (+) 741 WP_318018664.1 ABC transporter permease -
  R2B38_RS27585 (R2B38_27585) - 6094966..6096180 (+) 1215 WP_411978501.1 sensor histidine kinase -
  R2B38_RS27590 (R2B38_27590) vraR 6096177..6096791 (+) 615 WP_318018665.1 response regulator transcription factor Regulator
  R2B38_RS27595 (R2B38_27595) - 6096923..6097765 (-) 843 WP_318018666.1 transglutaminase-like domain-containing protein -
  R2B38_RS27600 (R2B38_27600) - 6097762..6098757 (-) 996 WP_318018667.1 GNAT family N-acetyltransferase -
  R2B38_RS27605 (R2B38_27605) fdxA 6098898..6099218 (+) 321 WP_019058397.1 ferredoxin -
  R2B38_RS27610 (R2B38_27610) - 6099338..6100432 (+) 1095 WP_318018668.1 bifunctional succinyldiaminopimelate transaminase/glutamate-prephenate aminotransferase -
  R2B38_RS27615 (R2B38_27615) - 6100569..6101021 (-) 453 WP_033286804.1 hypothetical protein -

Sequence

Protein


Download         Length: 204 a.a.        Molecular weight: 21577.82 Da        Isoelectric Point: 5.1224

>NTDB_id=822276 R2B38_RS27590 WP_318018665.1 6096177..6096791(+) (vraR) [Streptomyces sp. N50]
MSRTIKVLLAEDQSMVREALAALLGLEDDIEVVAQVARGDEVLEAARQHAVDVALLDIEMPGCTGIEAAAQVHKALPEVK
LVVLTTFGRPGYLRSAMEAGADAFLVKDAPAAQLAAAVRKVLAGERVIDPTLAAAALAEGANPLTDREREVLRAAADGST
NAELATALHLSQGTVRNYLSTAIQKLAVRNRAEAVRIAREKGWL

Nucleotide


Download         Length: 615 bp        

>NTDB_id=822276 R2B38_RS27590 WP_318018665.1 6096177..6096791(+) (vraR) [Streptomyces sp. N50]
ATGAGCCGCACGATCAAGGTCCTCCTCGCCGAGGACCAGTCGATGGTCCGCGAGGCACTGGCCGCACTCCTCGGCCTGGA
GGACGACATCGAGGTCGTCGCCCAAGTCGCCCGCGGCGACGAGGTGTTGGAGGCGGCCCGGCAACACGCCGTGGACGTGG
CCCTCCTCGACATCGAGATGCCGGGCTGCACGGGCATCGAGGCGGCGGCCCAGGTCCACAAGGCACTCCCCGAGGTGAAG
CTGGTGGTCCTGACGACCTTCGGCCGCCCCGGCTACCTCCGCAGCGCGATGGAGGCGGGAGCGGACGCCTTCCTCGTGAA
GGACGCCCCGGCGGCCCAACTGGCGGCAGCGGTACGGAAGGTACTCGCCGGTGAGCGGGTCATCGACCCCACCCTCGCGG
CAGCGGCCCTGGCGGAGGGCGCCAACCCGTTGACCGATCGCGAGCGGGAAGTACTGCGCGCGGCGGCGGACGGCTCGACG
AACGCGGAACTGGCGACGGCCCTCCACCTGTCCCAGGGCACGGTCCGCAACTACCTGTCGACAGCGATCCAGAAGCTGGC
GGTACGGAACAGGGCAGAGGCGGTACGCATCGCAAGGGAAAAGGGCTGGCTGTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(143-198)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

35.749

100

0.363