Detailed information NTG0822258

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: R2B38_RS21625
• Genome accession: NZ_CP137549
• Coordinates: 4850077..4852674 (+)
• Length: 865 a.a.
• NCBI ID: WP_318017709.1
• Uniprot ID: -
• Organism: Streptomyces sp. N50
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4845077..4857674

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R2B38_RS21595 (R2B38_21595)	-	4845662..4846729 (+)	1068	WP_318017704.1	helix-turn-helix transcriptional regulator	-
R2B38_RS21600 (R2B38_21600)	-	4846692..4847669 (-)	978	WP_318017705.1	helix-turn-helix transcriptional regulator	-
R2B38_RS21605 (R2B38_21605)	-	4847666..4848676 (-)	1011	WP_318017706.1	helix-turn-helix transcriptional regulator	-
R2B38_RS21610 (R2B38_21610)	-	4848819..4849022 (+)	204	WP_318017707.1	hypothetical protein	-
R2B38_RS21615 (R2B38_21615)	-	4849019..4849354 (+)	336	WP_026178811.1	hypothetical protein	-
R2B38_RS21620 (R2B38_21620)	-	4849495..4849944 (-)	450	WP_318017708.1	pyridoxamine 5'-phosphate oxidase family protein	-
R2B38_RS21625 (R2B38_21625)	clpC	4850077..4852674 (+)	2598	WP_318017709.1	ATP-dependent chaperone ClpB	Regulator
R2B38_RS21630 (R2B38_21630)	-	4852821..4853354 (+)	534	WP_033284794.1	YbjN domain-containing protein	-
R2B38_RS21635 (R2B38_21635)	-	4853440..4854645 (-)	1206	WP_318017710.1	pyridoxal phosphate-dependent aminotransferase	-
R2B38_RS21640 (R2B38_21640)	-	4854775..4855083 (+)	309	WP_318017711.1	hypothetical protein	-
R2B38_RS21645 (R2B38_21645)	-	4855624..4856160 (+)	537	WP_318017712.1	DUF2617 family protein	-

Sequence

Protein

• Length: 865 a.a.
• Molecular weight: 94344.54 Da
• Isoelectric Point: 4.6689

>NTDB_id=822258 R2B38_RS21625 WP_318017709.1 4850077..4852674(+) (clpC) [Streptomyces sp. N50]
MDAELTNRSRDAINAASNRAVTGGHADLTPAHLLLSLLEGQDNENITDLLAAVDADQAAVRSGAERVLGALPSVTGSTVA
PPQPNRELLAVIADAGERAKELGDDYLSTEHLLIGIAAKGGAAGDVISQQGAGAKKLLDAFQKSRGGRRVTTPDPEGQYK
ALEKFGTDFTAAAREGKLDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPESLKNKRLVS
LDLGAMVAGAKYRGEFEERLKTVLAEIKDSDGQIITFIDELHTVVGAGAGGDSSMDAGNMLKPMLARGELRMVGATTLDE
YRERIEKDPALERRFQQVLVAEPSVEDTIAILRGLKGRYEAHHKVVIADSALVAAATLSDRYITSRFLPDKAIDLVDEAA
SRLRMEIDSSPVEIDELQRSVDRLKMEELALDKETDAASIERLEKLRRDLADREEELRGLNARWEKEKQSLNRVGELKEK
LDELRGQAERAQRDGDFDTASKLLYGEIPSLERDLEEASQAEEEAAKDTMVKEEVGPDDIADVVGSWTGIPAGRLLEGET
QKLLRMEEELGRRLIGQREAVEAVSDAVRRTRAGIADPDRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMVRIDMSE
YGEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYSVILLDEVEKAHPEVFDVLLQVLDDGRLTDGQGRTVDFRNTILIL
TSNLGSNFLIDQTTGEDEKKDQVLQVVRASFKPEFLNRLDDLVVFSALNREELGRIAALQIGRLAKRLAERRLTLEISDE
ALTWLADNGNDPAYGARPLRRLVQTAIGDRLAKEILAGEVKDGDTVRVDAFGDGLIVGPATGKTL

Nucleotide

• Length: 2598 bp

>NTDB_id=822258 R2B38_RS21625 WP_318017709.1 4850077..4852674(+) (clpC) [Streptomyces sp. N50]
GTGGACGCCGAGCTGACCAACAGGAGCCGGGACGCGATCAACGCGGCCAGCAACCGTGCCGTGACCGGGGGGCACGCGGA
CCTGACCCCGGCGCACCTGCTGCTGTCCCTGCTGGAGGGCCAGGACAACGAGAACATCACCGACCTGCTCGCCGCCGTCG
ACGCCGACCAGGCCGCCGTACGGTCCGGGGCGGAGCGGGTGCTCGGCGCGCTGCCCAGCGTGACGGGCTCCACGGTCGCG
CCGCCGCAGCCCAACCGCGAGCTGCTCGCGGTGATCGCGGACGCCGGTGAGCGAGCGAAGGAGCTCGGCGACGACTACCT
CTCGACCGAGCACCTGCTGATCGGTATCGCCGCGAAGGGTGGCGCGGCCGGGGACGTAATCTCCCAGCAGGGGGCCGGCG
CGAAGAAGCTGCTGGACGCGTTCCAGAAGAGCAGGGGAGGGCGCCGGGTGACCACACCCGACCCCGAGGGGCAGTACAAG
GCGCTGGAGAAGTTCGGTACGGACTTCACGGCCGCCGCGCGCGAGGGCAAGCTCGACCCCGTCATCGGACGGGACCAGGA
GATCCGGCGGGTCGTGCAGGTGCTGTCCCGCCGCACCAAGAACAACCCCGTCCTCATCGGCGAGCCCGGCGTCGGCAAGA
CCGCCGTCGTCGAGGGGCTGGCCCAGCGGATCGTCAAGGGGGACGTGCCGGAGTCCCTCAAGAACAAGCGGCTGGTGTCG
CTGGACCTCGGCGCGATGGTCGCGGGCGCGAAGTACCGCGGCGAGTTCGAGGAGCGGCTCAAGACCGTCCTGGCCGAGAT
CAAGGACTCCGACGGCCAGATCATCACCTTCATCGACGAGCTGCACACCGTCGTGGGCGCGGGCGCCGGCGGCGACTCCT
CCATGGACGCCGGCAACATGCTGAAGCCGATGCTGGCCCGCGGCGAACTCCGCATGGTCGGCGCGACCACCCTCGACGAA
TACCGCGAACGCATCGAGAAGGACCCGGCGTTGGAGCGCCGCTTCCAGCAGGTGCTGGTCGCGGAGCCGAGCGTCGAGGA
CACGATCGCGATCCTGCGCGGCCTGAAGGGACGCTACGAAGCGCACCACAAGGTCGTCATCGCGGACAGCGCGCTGGTGG
CGGCCGCGACCCTCTCCGACCGCTACATCACCTCCCGCTTCCTCCCCGACAAGGCGATCGACCTGGTCGACGAGGCGGCG
TCCCGCCTCCGCATGGAGATCGACTCCTCCCCGGTCGAGATCGACGAACTCCAGCGCTCCGTCGACCGGTTGAAGATGGA
GGAGCTGGCCCTCGACAAGGAGACGGACGCCGCCTCCATCGAACGCCTGGAGAAGCTGCGCCGCGACCTCGCCGACCGCG
AGGAGGAGCTGCGCGGCCTCAACGCCCGCTGGGAGAAGGAGAAGCAGTCCCTCAACCGCGTCGGCGAGCTGAAGGAGAAG
CTCGACGAACTCCGCGGCCAGGCCGAACGCGCCCAGCGCGACGGCGACTTCGACACGGCGTCGAAACTTCTCTACGGCGA
GATCCCCTCCCTGGAACGGGACTTGGAGGAAGCCTCGCAGGCGGAGGAGGAAGCCGCCAAGGACACGATGGTCAAGGAAG
AGGTCGGCCCGGACGACATCGCGGACGTCGTCGGCTCCTGGACCGGCATCCCCGCAGGCCGCCTCCTGGAGGGCGAGACG
CAGAAACTCCTGCGCATGGAGGAGGAGTTGGGCCGCAGGCTCATCGGCCAGCGCGAGGCGGTGGAGGCGGTCTCGGACGC
CGTACGACGCACACGTGCGGGCATCGCGGACCCGGACCGTCCTACGGGCTCGTTCCTCTTCCTGGGCCCGACGGGCGTAG
GAAAGACGGAACTCGCCAAAGCCCTGGCGGACTTCCTCTTCGACGACGAACGGGCCATGGTCCGCATCGACATGTCGGAG
TACGGCGAGAAGCACAGCGTGGCCCGGCTGGTCGGTGCCCCGCCCGGCTACGTCGGCTACGAGGAGGGCGGCCAGCTCAC
GGAGGCGGTGCGCAGGCGCCCGTACTCGGTGATCCTGCTCGACGAGGTGGAGAAGGCGCACCCCGAGGTCTTCGACGTGC
TGCTCCAGGTACTGGACGACGGCCGCCTGACCGACGGCCAGGGCCGCACGGTCGACTTCCGCAACACGATCCTGATCCTC
ACGTCCAACCTGGGCAGCAACTTCCTGATCGACCAGACCACGGGCGAGGACGAGAAGAAGGACCAGGTCCTGCAGGTGGT
CCGCGCGTCCTTCAAGCCGGAGTTCCTGAACCGGCTGGACGACCTGGTGGTCTTCTCCGCCCTGAACCGGGAGGAGCTGG
GCCGTATCGCGGCTCTCCAGATCGGCCGCCTGGCGAAGAGGCTGGCTGAGCGCCGCCTCACCCTGGAGATCAGCGACGAG
GCCCTGACCTGGCTCGCGGACAACGGCAACGACCCGGCGTACGGCGCGCGCCCGCTGCGCCGGCTGGTGCAGACGGCGAT
CGGCGACCGGCTCGCGAAGGAGATCCTGGCGGGGGAGGTCAAGGACGGGGACACGGTGCGGGTGGATGCGTTCGGGGACG
GGCTGATCGTGGGGCCGGCGACGGGGAAGACGCTGTAG

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (768-848)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-338)

• AAA lid domain (AAA_lid_9) (344-446)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-761)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-146)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (23-69)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.636	100	0.444
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.197	82.081	0.379
clpC	Lactococcus lactis subsp. cremoris KW2	46.465	80.116	0.372