Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   R2B38_RS08235 Genome accession   NZ_CP137549
Coordinates   1921910..1924888 (-) Length   992 a.a.
NCBI ID   WP_318015629.1    Uniprot ID   -
Organism   Streptomyces sp. N50     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1916910..1929888
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2B38_RS08210 (R2B38_08210) - 1917631..1918002 (+) 372 WP_318015624.1 response regulator -
  R2B38_RS08215 (R2B38_08215) - 1918216..1919163 (+) 948 WP_318015625.1 hypothetical protein -
  R2B38_RS08220 (R2B38_08220) - 1919200..1919622 (-) 423 WP_318015626.1 Rieske (2Fe-2S) protein -
  R2B38_RS08225 (R2B38_08225) - 1919844..1920929 (+) 1086 WP_318015627.1 LacI family DNA-binding transcriptional regulator -
  R2B38_RS08230 (R2B38_08230) - 1920926..1921837 (+) 912 WP_318015628.1 carbohydrate kinase -
  R2B38_RS08235 (R2B38_08235) uvrA 1921910..1924888 (-) 2979 WP_318015629.1 excinuclease ABC subunit UvrA Machinery gene
  R2B38_RS08240 (R2B38_08240) - 1925114..1925800 (+) 687 WP_318015630.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  R2B38_RS08245 (R2B38_08245) - 1925795..1926085 (-) 291 WP_318015631.1 hypothetical protein -
  R2B38_RS08250 (R2B38_08250) - 1926202..1926858 (+) 657 WP_318015632.1 MBL fold metallo-hydrolase -
  R2B38_RS08255 (R2B38_08255) - 1927184..1928068 (+) 885 WP_318015633.1 ABC transporter substrate-binding protein -
  R2B38_RS08260 (R2B38_08260) - 1928065..1928982 (+) 918 WP_318015634.1 amino acid ABC transporter permease -
  R2B38_RS08265 (R2B38_08265) - 1928979..1929740 (+) 762 WP_318015635.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 992 a.a.        Molecular weight: 108933.92 Da        Isoelectric Point: 7.1455

>NTDB_id=822237 R2B38_RS08235 WP_318015629.1 1921910..1924888(-) (uvrA) [Streptomyces sp. N50]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECGRPISRQSPQAVVDKVLALPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGETIQLSEPPTLKKQEKHTIEVVIDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCPYDDLSFEELEPRSFSFNSPFGACPECSGIGTRMEVDAELIVPDEDKSLDEGAIHPWSHGHTK
DYFSRLIGALADALGFRTDIPFAGLPQRAKKALLYGHKTQIEVRYRNRYGRERVYTTPFEGAVPFVKRRHGEAESDASRE
RFEGYMREVPCPTCHGTRLKPVVLAVTIMDKSIAEISGMSISDCAEFLGGMKLDARDKKIAERVLKECNERLRFLVDVGL
DYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVAD
WIVDIGPGAGEHGGKVVHSGSLKELLANEESMTGQYLSGKKAIPLPEIRRPLDPSRRLTVHGARENNLQDIDVSFPLGVF
TAVTGVSGSGKSTLVNDILYTHLARELNGARNVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRKLFA
ETTEAKVRGYLPGRFSFNVKGGRCENCAGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLDVHYKGKSIADVLNMPIEEA
TEFFEAVPGIARHLNTLKDVGLGYVRLGQSATTLSGGEAQRVKLASELQRRSTGRTVYVLDEPTTGLHFEDISKLLTVLG
GLVDKGNTVIVIEHNLDVIKVADWVVDMGPEGGAGGGLVIAEGTPEQVAAVSTSHTGKFLREILDADRISDGAPVKAPRK
TAAKKTAAVPAKKSAPAKKATPAKKTTRARKA

Nucleotide


Download         Length: 2979 bp        

>NTDB_id=822237 R2B38_RS08235 WP_318015629.1 1921910..1924888(-) (uvrA) [Streptomyces sp. N50]
GTGGCCGACCGTCTCATCGTCCGTGGCGCGCGCGAGCACAATCTGAAGAATGTCTCGCTCGACCTTCCACGCGACTCGCT
CATCGTGTTCACGGGCCTGTCCGGGTCGGGCAAGTCCTCCCTGGCCTTCGACACGATCTTCGCCGAGGGCCAGCGGCGCT
ACGTGGAATCGCTCTCCTCGTACGCCCGCCAGTTCCTCGGCCAGATGGACAAGCCGGACGTCGACTTCATCGAGGGTCTC
TCCCCGGCCGTCTCCATCGACCAGAAGTCGACCTCGCGCAACCCGCGCTCGACGGTCGGCACCATCACCGAGGTCTACGA
CTACCTGCGCCTGCTCTTCGCGCGCATCGGCAAGCCGCACTGCCCGGAGTGCGGTCGGCCCATCTCGCGCCAGTCGCCGC
AGGCCGTCGTCGACAAGGTCCTGGCGCTGCCCGAGGGAAGCCGCTTCCAGGTCCTGTCGCCGCTGGTGCGCGAGCGCAAG
GGCGAGTTCGTCGACCTGTTCGCGGACCTCCAGACCAAGGGCTACAGCCGCGCGCGCGTGGACGGCGAGACCATCCAGCT
CTCCGAGCCGCCCACCCTGAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCATCGACCGCCTCACGGTGAAGGACTCCG
CCAAGCGCCGCCTCACCGACTCCGTGGAGACCGCCCTCGGGCTGTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGCGAGCGCATGTACTCGGAGCACCTGTACTGCCCGTACGACGACCTGTCCTTCGAGGAGCT
GGAGCCCCGCTCCTTCTCCTTCAACTCGCCCTTCGGCGCCTGCCCCGAGTGCTCCGGCATCGGCACGCGCATGGAGGTCG
ACGCCGAGCTGATCGTCCCGGACGAGGACAAGTCCCTGGACGAGGGCGCCATCCACCCGTGGTCGCACGGCCACACCAAG
GACTACTTCAGCCGCCTCATCGGCGCCCTCGCGGACGCGCTGGGCTTCCGCACCGACATCCCCTTCGCGGGTCTCCCGCA
GCGCGCCAAGAAGGCCCTGCTGTACGGCCACAAGACGCAGATCGAGGTGCGGTACCGGAACAGGTACGGCCGCGAGCGGG
TCTACACGACGCCCTTCGAAGGCGCCGTCCCCTTCGTGAAGCGGCGGCACGGCGAGGCGGAGAGCGACGCCAGCCGCGAG
CGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCCACCTGTCACGGCACGCGCCTGAAGCCCGTCGTCCTCGCGGTCAC
GATCATGGACAAGTCGATCGCCGAGATCTCCGGCATGTCCATCAGCGACTGCGCGGAGTTCCTCGGCGGGATGAAGCTCG
ACGCCCGCGACAAGAAGATCGCCGAGCGCGTGCTGAAGGAGTGCAACGAGAGGCTGCGCTTCCTGGTCGACGTAGGCCTC
GACTACCTCTCGCTGAACCGCGCGGCCGGCACCCTCTCCGGCGGCGAGGCCCAGCGCATCCGCCTGGCCACCCAGATCGG
CTCCGGACTCGTGGGCGTCCTGTACGTCCTCGACGAGCCGTCCATCGGCCTGCACCAGCGCGACAACCACCGGCTGATCG
AGACCCTGGTCCGGCTCCGCGACATGGGCAACACGCTCATCGTCGTCGAGCACGACGAGGACACCATCAAGGTCGCCGAC
TGGATCGTCGACATCGGCCCCGGCGCGGGCGAGCACGGCGGCAAGGTCGTGCACAGCGGCTCCCTGAAGGAGCTGCTCGC
CAACGAGGAGTCGATGACCGGGCAGTACCTGTCCGGCAAGAAGGCCATCCCGCTGCCCGAGATCCGGCGCCCGCTCGACC
CCTCCCGCCGGCTCACGGTGCACGGCGCCCGGGAGAACAACCTTCAGGACATCGACGTCTCGTTCCCCCTGGGCGTGTTC
ACCGCGGTCACCGGCGTCTCCGGCTCCGGCAAGTCGACCCTGGTCAACGACATCCTGTACACACACCTGGCCCGCGAGCT
GAACGGCGCGAGGAACGTGCCGGGACGGCACACGCGCGTGGACGGCGACGACCTCGTCGACAAGGTCGTGCACGTCGACC
AGTCGCCCATCGGCCGCACCCCGCGGTCGAACCCGGCGACGTACACCGGAGTCTTCGACCACGTCCGCAAGCTGTTCGCG
GAGACGACCGAGGCGAAGGTGCGGGGCTATCTGCCCGGCCGCTTCTCGTTCAACGTCAAGGGCGGCCGCTGCGAGAACTG
CGCGGGCGACGGCACCATCAAGATCGAGATGAACTTCCTGCCGGACGTGTACGTCCCGTGCGAGGTGTGCCACGGCGCCC
GCTACAACCGGGAGACGCTGGACGTCCACTACAAGGGCAAGTCCATCGCCGACGTCCTGAACATGCCGATCGAGGAGGCC
ACGGAGTTCTTCGAGGCGGTCCCCGGGATCGCCCGCCACCTCAACACCCTCAAGGACGTCGGCCTCGGCTACGTCCGCCT
CGGCCAGTCCGCGACCACCCTGTCCGGCGGTGAGGCCCAGCGCGTCAAGCTCGCCAGCGAGCTCCAGCGCCGCTCCACCG
GCCGTACGGTCTACGTCCTGGACGAGCCGACCACCGGCCTGCACTTCGAGGACATCAGCAAGCTCCTCACGGTGCTCGGC
GGCCTGGTCGACAAGGGCAACACGGTCATCGTCATCGAGCACAACCTCGACGTGATCAAGGTCGCCGACTGGGTCGTCGA
CATGGGTCCGGAGGGTGGCGCGGGCGGCGGTCTCGTCATCGCCGAGGGCACACCGGAGCAGGTTGCCGCAGTCTCGACCA
GCCACACCGGCAAGTTCCTCCGCGAGATCCTCGACGCCGACCGGATCAGCGACGGAGCCCCCGTGAAGGCCCCGCGCAAG
ACGGCCGCCAAGAAGACCGCGGCGGTACCGGCGAAGAAGTCCGCGCCCGCGAAGAAGGCCACGCCCGCGAAGAAGACGAC
GCGGGCCCGCAAGGCCTGA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-403)

ABC transporter (ABC_tran)

(628-864)

UvrA interaction domain (UvrA_inter)

(131-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

56.825

95.262

0.541
  uvrA Streptococcus pneumoniae TIGR4

56.825

95.262

0.541
  uvrA Streptococcus pneumoniae D39

56.825

95.262

0.541