Detailed information NTG0822113

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QFX63_RS09565
• Genome accession: NZ_CP123741
• Coordinates: 1940101..1941144 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 2.2
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1935101..1946144

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QFX63_RS09535	-	1935523..1936779 (-)	1257	WP_001789555.1	aminopeptidase	-
QFX63_RS09540	-	1936782..1936982 (-)	201	WP_000180460.1	DUF1128 family protein	-
QFX63_RS09545	-	1937129..1937593 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QFX63_RS09550	-	1937600..1937875 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QFX63_RS09555	-	1938153..1939370 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
QFX63_RS09560	vraR	1939482..1940111 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QFX63_RS09565	vraS	1940101..1941144 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QFX63_RS09570	liaF	1941141..1941842 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QFX63_RS09575	-	1941857..1942243 (-)	387	WP_001110179.1	hypothetical protein	-
QFX63_RS09580	map	1942460..1943218 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QFX63_RS09585	-	1943808..1944794 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
QFX63_RS09590	-	1945225..1945638 (-)	414	WP_001566709.1	hypothetical protein	-
QFX63_RS09595	-	1945667..1945778 (-)	112	Protein_1854	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=822113 QFX63_RS09565 WP_001017131.1 1940101..1941144(-) (vraS) [Staphylococcus aureus strain 2.2]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=822113 QFX63_RS09565 WP_001017131.1 1940101..1941144(-) (vraS) [Staphylococcus aureus strain 2.2]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1