Detailed information NTG0822078

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QFX50_RS13370
• Genome accession: NZ_CP123740
• Coordinates: 2682883..2683926 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 2.3b
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2677883..2688926

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QFX50_RS13340	-	2678305..2679561 (-)	1257	WP_001789555.1	aminopeptidase	-
QFX50_RS13345	-	2679564..2679764 (-)	201	WP_000180460.1	DUF1128 family protein	-
QFX50_RS13350	-	2679911..2680375 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QFX50_RS13355	-	2680382..2680657 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QFX50_RS13360	-	2680935..2682152 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
QFX50_RS13365	vraR	2682264..2682893 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QFX50_RS13370	vraS	2682883..2683926 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QFX50_RS13375	liaF	2683923..2684624 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QFX50_RS13380	-	2684639..2685025 (-)	387	WP_001110179.1	hypothetical protein	-
QFX50_RS13385	map	2685242..2686000 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QFX50_RS13390	-	2686590..2687576 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
QFX50_RS13395	-	2688007..2688420 (-)	414	WP_001566709.1	hypothetical protein	-
QFX50_RS13400	-	2688449..2688560 (-)	112	Protein_2602	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=822078 QFX50_RS13370 WP_001017131.1 2682883..2683926(-) (vraS) [Staphylococcus aureus strain 2.3b]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=822078 QFX50_RS13370 WP_001017131.1 2682883..2683926(-) (vraS) [Staphylococcus aureus strain 2.3b]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1