Detailed information NTG0821990

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QFX56_RS09555
• Genome accession: NZ_CP123738
• Coordinates: 1934732..1935775 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 2.6
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1929732..1940775

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QFX56_RS09525	-	1930154..1931410 (-)	1257	WP_001789555.1	aminopeptidase	-
QFX56_RS09530	-	1931413..1931613 (-)	201	WP_000180460.1	DUF1128 family protein	-
QFX56_RS09535	-	1931760..1932224 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QFX56_RS09540	-	1932231..1932506 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QFX56_RS09545	-	1932784..1934001 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
QFX56_RS09550	vraR	1934113..1934742 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QFX56_RS09555	vraS	1934732..1935775 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QFX56_RS09560	liaF	1935772..1936473 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QFX56_RS09565	-	1936488..1936874 (-)	387	WP_001110179.1	hypothetical protein	-
QFX56_RS09570	map	1937091..1937849 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QFX56_RS09575	-	1938439..1939425 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
QFX56_RS09580	-	1939856..1940269 (-)	414	WP_001566709.1	hypothetical protein	-
QFX56_RS09585	-	1940298..1940409 (-)	112	Protein_1855	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=821990 QFX56_RS09555 WP_001017131.1 1934732..1935775(-) (vraS) [Staphylococcus aureus strain 2.6]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=821990 QFX56_RS09555 WP_001017131.1 1934732..1935775(-) (vraS) [Staphylococcus aureus strain 2.6]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1