Detailed information NTG0821271

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: R5020_RS12570
• Genome accession: NZ_CP137500
• Coordinates: 2630761..2633325 (+)
• Length: 854 a.a.
• NCBI ID: WP_003094682.1
• Uniprot ID: A0A0H2ZHB4
• Organism: Pseudomonas aeruginosa strain HPA0384
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2625761..2638325

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R5020_RS12545 (R5020_12545)	pilS	2625763..2627355 (-)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
R5020_RS12550 (R5020_12550)	-	2627345..2627590 (-)	246	WP_014603563.1	PP0621 family protein	-
R5020_RS12555 (R5020_12555)	-	2627747..2628772 (-)	1026	WP_003094687.1	outer membrane protein assembly factor BamD	-
R5020_RS12560 (R5020_12560)	rluD	2628918..2629880 (+)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
R5020_RS12565 (R5020_12565)	pgeF	2629877..2630605 (+)	729	WP_003094684.1	peptidoglycan editing factor PgeF	-
R5020_RS12570 (R5020_12570)	clpC	2630761..2633325 (+)	2565	WP_003094682.1	ATP-dependent chaperone ClpB	Regulator
R5020_RS12590 (R5020_12590)	-	2634178..2635461 (-)	1284	WP_019726896.1	site-specific integrase	-
R5020_RS12595 (R5020_12595)	mobH	2635458..2637377 (-)	1920	WP_019726895.1	MobH family relaxase	-
R5020_RS12600 (R5020_12600)	-	2637396..2637710 (-)	315	WP_149127250.1	hypothetical protein	-

Sequence

Protein

• Length: 854 a.a.
• Molecular weight: 95005.65 Da
• Isoelectric Point: 5.1331

>NTDB_id=821271 R5020_RS12570 WP_003094682.1 2630761..2633325(+) (clpC) [Pseudomonas aeruginosa strain HPA0384]
MRIDRLTSKLQLALSDAQSLAVGHDHPAIEPVHLLSALLEQQGGSIKPLLMQVGFDIAALRSGLNKELDALPKIQSPTGD
VNLSQDLARLLNQADRLAQQKGDQFISSELVLLAAMDENTRLGKLLLGQGVSRKALENAVANLRGGEAVNDPNVEESRQA
LDKYTVDMTKRAEEGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPDGLKDKRLLAL
DMGALIAGAKFRGEFEERLKAVLNELGKQEGRVILFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPSEEDTIAILRGLKERYEVHHGVSITDGAIIAAAKLSHRYITDRQLPDKAIDLIDEAASR
IRMEIDSKPEELDRLDRRLIQLKIEREALKKEDDEATRKRLAKLEEDIVKLEREYADLEEIWKSEKAEVQGSAQIQQKIE
QAKQEMEAARRKGDLESMARIQYQTIPDLERSLQMVDQHGKTENQLLRNKVTDEEIAEVVSKWTGIPVSKMLEGEREKLL
RMEQELHRRVIGQDEAVVAVSNAVRRSRAGLADPNRPSGSFLFLGPTGVGKTELCKALAEFLFDTEEALVRIDMSEFMEK
HSVARLIGAPPGYVGFEEGGYLTEAIRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRLTDSHGRTVDFRNTVVVMTSNL
GSAQIQELAGDREAQRAAVMDAVNAHFRPEFINRIDEVVVFEPLAREQIAGIAEIQLGRLRKRLAERELSLELSQEALDK
LIAVGFDPVYGARPLKRAIQRWIENPLAQLILAGKFAPGASISAKVEGDEIVFA

Nucleotide

• Length: 2565 bp

>NTDB_id=821271 R5020_RS12570 WP_003094682.1 2630761..2633325(+) (clpC) [Pseudomonas aeruginosa strain HPA0384]
ATGCGAATAGACCGTTTGACCAGCAAGCTGCAACTGGCGCTCTCCGACGCCCAGTCCCTGGCCGTTGGCCATGACCATCC
GGCCATCGAGCCGGTGCACCTGCTTTCCGCCCTGCTCGAGCAGCAAGGCGGTTCGATCAAGCCCCTGCTGATGCAGGTCG
GCTTCGATATCGCCGCCCTGCGCAGCGGCCTCAACAAAGAACTCGACGCGCTGCCGAAGATCCAGAGCCCGACCGGCGAC
GTGAACCTGTCCCAGGATCTCGCACGCCTGCTCAACCAGGCTGACCGCCTGGCCCAGCAGAAGGGCGACCAGTTCATCTC
CAGCGAGCTGGTATTGCTGGCCGCGATGGACGAGAACACCAGGCTCGGCAAGCTGCTGCTCGGCCAGGGCGTGTCGCGCA
AGGCGCTGGAGAATGCTGTGGCCAACCTGCGTGGCGGCGAAGCGGTGAACGACCCGAACGTCGAGGAGTCGCGCCAGGCG
CTGGACAAGTACACCGTCGACATGACCAAGCGCGCCGAGGAAGGCAAGCTCGACCCGGTGATCGGTCGCGACGACGAGAT
CCGCCGGACCATCCAGGTCCTGCAGCGGCGGACCAAGAACAACCCGGTGCTGATCGGCGAACCCGGCGTCGGCAAGACCG
CCATCGTCGAGGGCCTGGCCCAGCGCATCATCAACGGCGAAGTGCCGGACGGCCTCAAGGACAAGCGCCTGCTGGCCCTG
GACATGGGGGCGCTGATCGCCGGTGCCAAGTTCCGCGGCGAGTTCGAGGAACGCCTGAAGGCGGTCCTCAACGAACTGGG
CAAGCAGGAAGGCCGGGTCATCCTGTTCATCGACGAACTGCACACCATGGTCGGCGCCGGCAAGGCGGAAGGTGCCATGG
ACGCCGGCAACATGCTCAAGCCGGCTCTGGCGCGCGGCGAGCTGCACTGCGTCGGTGCTACTACCCTCGACGAGTATCGC
CAGTACATCGAGAAGGATGCCGCGCTGGAGCGCCGCTTCCAGAAGGTACTGGTGGACGAACCGAGCGAGGAAGACACGAT
CGCCATCCTCCGTGGTCTCAAGGAACGCTATGAAGTGCACCACGGGGTGAGCATCACCGACGGCGCGATCATCGCCGCGG
CCAAGCTGTCGCACCGCTACATCACCGATCGGCAACTGCCGGACAAGGCCATCGACCTGATCGACGAGGCCGCCAGCCGC
ATCCGCATGGAGATCGACTCCAAGCCGGAGGAACTGGATCGTCTCGACCGTCGCCTGATCCAGCTGAAGATCGAGCGCGA
GGCGCTGAAGAAGGAAGACGACGAAGCCACCAGGAAGCGCCTGGCCAAGCTGGAGGAGGATATCGTCAAGCTCGAGCGCG
AATACGCCGACCTCGAGGAGATCTGGAAGTCCGAGAAGGCCGAGGTACAGGGCTCGGCGCAGATCCAGCAGAAGATCGAG
CAGGCCAAGCAGGAAATGGAGGCGGCGCGGCGCAAGGGCGACCTCGAGAGCATGGCGCGCATCCAGTACCAGACCATCCC
TGACCTGGAGCGCAGCCTGCAGATGGTCGACCAGCACGGCAAGACCGAGAACCAGTTGCTGCGCAACAAGGTGACCGACG
AGGAAATCGCCGAAGTGGTTTCCAAGTGGACCGGTATCCCGGTGTCGAAGATGCTCGAGGGCGAGCGCGAGAAGCTGCTG
CGCATGGAGCAGGAGCTGCATCGGCGAGTGATCGGCCAGGACGAGGCGGTAGTCGCCGTGTCCAACGCCGTGCGCCGTTC
GCGCGCCGGCCTCGCCGATCCGAACCGGCCGAGCGGCTCGTTCCTCTTCCTCGGCCCGACCGGGGTGGGCAAGACCGAGT
TGTGCAAGGCGCTGGCCGAGTTCCTCTTCGATACCGAGGAGGCGCTGGTGCGGATAGATATGTCCGAGTTCATGGAGAAA
CACTCGGTGGCCCGCCTGATCGGCGCGCCTCCGGGCTACGTCGGCTTCGAGGAAGGCGGCTACCTGACCGAGGCGATCCG
CCGCAAGCCCTACTCGGTGGTGCTGTTGGACGAGGTGGAGAAGGCCCATCCGGATGTATTCAACATTCTCCTCCAGGTGC
TCGAGGACGGACGCCTGACCGACAGTCACGGGCGTACGGTGGACTTCCGCAACACCGTGGTGGTGATGACCTCCAACCTC
GGTTCGGCGCAGATCCAGGAGCTGGCCGGCGACCGCGAGGCGCAACGTGCCGCAGTGATGGACGCGGTCAATGCGCACTT
CCGTCCGGAATTCATCAACCGGATCGACGAAGTGGTGGTGTTCGAGCCGCTGGCTCGCGAGCAGATCGCCGGCATCGCCG
AGATCCAGCTCGGTCGCCTGCGCAAGCGCCTGGCCGAGCGCGAGCTGAGCCTGGAACTGAGCCAGGAGGCGCTGGACAAG
CTGATTGCCGTCGGCTTCGACCCGGTCTATGGCGCACGCCCGCTGAAGCGGGCCATCCAGCGCTGGATCGAGAACCCGCT
GGCGCAACTGATCCTGGCCGGCAAATTCGCGCCGGGTGCCAGTATCTCGGCGAAGGTGGAAGGCGACGAGATCGTCTTCG
CCTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-444)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (764-842)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-334)

3D structure

• AlphaFold DB: A0A0H2ZHB4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	48.391	100	0.493
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.417	100	0.436