Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   R4705_RS07080 Genome accession   NZ_CP137115
Coordinates   1334585..1336690 (+) Length   701 a.a.
NCBI ID   WP_001063431.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20614-6     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1329585..1341690
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4705_RS07065 ftsL 1330421..1330738 (+) 318 WP_000818547.1 cell division protein FtsL -
  R4705_RS07070 pbp2X 1330742..1332994 (+) 2253 WP_000872267.1 penicillin-binding protein 2X -
  R4705_RS07075 mraY 1332996..1333976 (+) 981 WP_000470794.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
  R4705_RS07080 clpC 1334585..1336690 (+) 2106 WP_001063431.1 AAA family ATPase Regulator
  R4705_RS07085 - 1336986..1337468 (-) 483 WP_000032550.1 S-ribosylhomocysteine lyase -
  R4705_RS07090 - 1337563..1339047 (-) 1485 WP_279513694.1 DUF1846 domain-containing protein -
  R4705_RS07095 - 1339199..1340806 (+) 1608 WP_001156819.1 alpha-glucosidase -
  R4705_RS07100 - 1340965..1341138 (+) 174 WP_001022221.1 hypothetical protein -
  R4705_RS07105 - 1341131..1341659 (-) 529 Protein_1352 transposase -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77697.48 Da        Isoelectric Point: 4.7080

>NTDB_id=820255 R4705_RS07080 WP_001063431.1 1334585..1336690(+) (clpC) [Streptococcus pneumoniae strain 20614-6]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRTTGQLPGNAETDVQMPQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTCGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QVAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=820255 R4705_RS07080 WP_001063431.1 1334585..1336690(+) (clpC) [Streptococcus pneumoniae strain 20614-6]
ATGAATAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGCCGTTACTTAATTAATGGACGCGAAGTCACACCTGAGGAATTTGCTCACTATCGTACGACTGGTCAATTAC
CAGGAAATGCAGAAACTGATGTGCAAATGCCACAACAGGCATCAGGTATGAAACAAGACGGTGTCCTTGCAAAACTAGGT
CGAAACTTGACAGCAGAAGCGCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGCCGCACCAAGAACAATCCTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCAGTTGTCGAAGGTC
TAGCGCAAGCCATTGTGAACGGAGATGTTCCTGCTGCTATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTTGTGGAGACAGTGGTTCTAAAGGGCTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCAGCAGAGAATACTTTTAAAATTCT
TCAAGGCATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACGGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAGGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGCTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAGCTTCCTCTTTGTAGGGTCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGATCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGTTTTCACACTTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTCAGT
CAAGTGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGCGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTAGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAGAAAGCCTAA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)

AAA lid domain (AAA_lid_9)

(259-354)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

47.578

100

0.476
  clpE Streptococcus mutans UA159

49.221

91.583

0.451
  clpE Streptococcus pneumoniae Rx1

47.785

90.157

0.431
  clpE Streptococcus pneumoniae D39

47.785

90.157

0.431
  clpE Streptococcus pneumoniae R6

47.785

90.157

0.431
  clpE Streptococcus pneumoniae TIGR4

47.709

90.3

0.431
  clpC Bacillus subtilis subsp. subtilis str. 168

43.935

96.434

0.424
  clpC Streptococcus pneumoniae Rx1

41.911

92.582

0.388
  clpC Streptococcus pneumoniae D39

41.911

92.582

0.388
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

41.846

92.725

0.388
  clpC Streptococcus pneumoniae TIGR4

41.757

92.582

0.387
  clpC Streptococcus thermophilus LMD-9

42.338

90.3

0.382
  clpC Streptococcus thermophilus LMG 18311

42.18

90.3

0.381
  clpC Streptococcus mutans UA159

41.909

88.16

0.369