Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   R4701_RS04370 Genome accession   NZ_CP137114
Coordinates   866080..866520 (+) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain 15P3054     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 861080..871520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS04345 ribE 861122..861757 (+) 636 WP_317806001.1 riboflavin synthase -
  R4701_RS04350 - 861777..862982 (+) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  R4701_RS04355 ribE 862983..863450 (+) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  R4701_RS04360 hexB 863775..865724 (-) 1950 WP_000018169.1 DNA mismatch repair endonuclease MutL Machinery gene
  R4701_RS04365 - 865867..865992 (+) 126 WP_001813544.1 hypothetical protein -
  R4701_RS04370 brsR 866080..866520 (+) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  R4701_RS04375 - 866517..866975 (+) 459 WP_000745054.1 DUF3021 domain-containing protein -
  R4701_RS04380 - 867285..868547 (+) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  R4701_RS04385 nrdI 868840..869310 (-) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  R4701_RS04390 - 869388..869921 (-) 534 WP_000729029.1 hypothetical protein -
  R4701_RS04395 - 869973..871259 (-) 1287 WP_050232545.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=820095 R4701_RS04370 WP_000861956.1 866080..866520(+) (brsR) [Streptococcus pneumoniae strain 15P3054]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=820095 R4701_RS04370 WP_000861956.1 866080..866520(+) (brsR) [Streptococcus pneumoniae strain 15P3054]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363