Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   R4701_RS03555 Genome accession   NZ_CP137114
Coordinates   713146..715251 (-) Length   701 a.a.
NCBI ID   WP_317805990.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15P3054     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 708146..720251
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS03535 - 708697..708870 (-) 174 WP_001022228.1 S-ribosylhomocysteinase -
  R4701_RS03540 - 709029..710636 (-) 1608 WP_317805988.1 alpha-glucosidase -
  R4701_RS03545 - 710789..712273 (+) 1485 WP_317805989.1 DUF1846 domain-containing protein -
  R4701_RS03550 - 712368..712850 (+) 483 WP_000032550.1 S-ribosylhomocysteine lyase -
  R4701_RS03555 clpC 713146..715251 (-) 2106 WP_317805990.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  R4701_RS03560 mraY 715809..716789 (-) 981 WP_000470833.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
  R4701_RS03565 pbp2X 716791..719043 (-) 2253 WP_000872267.1 penicillin-binding protein 2X -
  R4701_RS03570 ftsL 719047..719364 (-) 318 WP_000818547.1 cell division protein FtsL -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77551.27 Da        Isoelectric Point: 4.6567

>NTDB_id=820089 R4701_RS03555 WP_317805990.1 713146..715251(-) (clpC) [Streptococcus pneumoniae strain 15P3054]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAYYRATGQLPGNAESDVQMQQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQEASEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIVSIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVIPLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=820089 R4701_RS03555 WP_317805990.1 713146..715251(-) (clpC) [Streptococcus pneumoniae strain 15P3054]
ATGAACAACAATTTTAATAATTTTAACAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGACGTTACTTGATTAATGGACGTGAAGTGACACCTGAGGAATTTGCTTACTATCGTGCAACTGGTCAATTGC
CAGGAAATGCAGAATCTGATGTGCAAATGCAACAACAGGCTTCAGGTATGAAACAAGATGGTGTCCTTGCTAAACTGGGT
CGAAACTTGACAGCAGAAGCGCGTGAGGGCAAGCTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAGCATCTGA
AATCCTCTCACGCCGTACCAAGAACAATCCTGTTTTAGTCGGAGACGCAGGTGTTGGTAAGACAGCCGTTGTCGAAGGCC
TAGCGCAAGCGATTGTGAACGGCGATGTCCCAGCTGCTATTAAGAACAAGGAAATTGTTTCCATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGGCTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCGGCAGAGAATACTTTTAAAATTCT
TCAAGGAATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACAGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGCTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAGCTTCCTCTTTGTAGGGTCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGATCCTCAAG
TTATTCCCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACAATTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTCAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGAGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTAGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAGAAAGCCTAA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)

AAA lid domain (AAA_lid_9)

(259-354)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

49.844

91.298

0.455
  clpE Streptococcus mutans UA159

49.456

91.726

0.454
  clpE Streptococcus pneumoniae TIGR4

47.792

90.442

0.432
  clpE Streptococcus pneumoniae Rx1

47.792

90.442

0.432
  clpE Streptococcus pneumoniae D39

47.792

90.442

0.432
  clpE Streptococcus pneumoniae R6

47.792

90.442

0.432
  clpC Bacillus subtilis subsp. subtilis str. 168

44.838

92.582

0.415
  clpC Streptococcus pneumoniae Rx1

42.766

89.729

0.384
  clpC Streptococcus pneumoniae D39

42.766

89.729

0.384
  clpC Streptococcus pneumoniae TIGR4

42.607

89.729

0.382
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.112

88.017

0.379
  clpC Streptococcus thermophilus LMD-9

42.903

88.445

0.379
  clpC Streptococcus thermophilus LMG 18311

42.742

88.445

0.378
  clpC Streptococcus mutans UA159

41.909

88.16

0.369