Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   R4701_RS00395 Genome accession   NZ_CP137114
Coordinates   94848..95312 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain 15P3054     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 89848..100312
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS00375 - 90799..91767 (-) 969 WP_050254897.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  R4701_RS00380 pdrM 91921..93282 (-) 1362 WP_050254896.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  R4701_RS00385 - 93293..93553 (-) 261 WP_001105925.1 hypothetical protein -
  R4701_RS00390 - 93567..94835 (-) 1269 WP_000924497.1 dihydroorotase -
  R4701_RS00395 mutX 94848..95312 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  R4701_RS00400 - 95322..95975 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  R4701_RS00405 - 96111..96713 (-) 603 WP_001812270.1 hypothetical protein -
  R4701_RS00410 - 96771..97484 (-) 714 WP_000499426.1 YjjG family noncanonical pyrimidine nucleotidase -
  R4701_RS00415 dhaM 97943..98335 (-) 393 WP_373274838.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  R4701_RS00420 - 98322..98396 (-) 75 Protein_83 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=820059 R4701_RS00395 WP_001135768.1 94848..95312(-) (mutX) [Streptococcus pneumoniae strain 15P3054]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=820059 R4701_RS00395 WP_001135768.1 94848..95312(-) (mutX) [Streptococcus pneumoniae strain 15P3054]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGACGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987