Detailed information NTG0820041

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: R4707_RS09820
• Genome accession: NZ_CP137113
• Coordinates: 1867622..1869880 (-)
• Length: 752 a.a.
• NCBI ID: WP_081543116.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain ZGX
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1862622..1874880

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4707_RS09800	tnpB	1864988..1865203 (-)	216	WP_000376913.1	IS66 family insertion sequence element accessory protein TnpB	-
R4707_RS09805	-	1865572..1865871 (-)	300	WP_000767195.1	DUF1827 family protein	-
R4707_RS09810	-	1866036..1866487 (-)	452	Protein_1894	NUDIX hydrolase	-
R4707_RS09815	-	1866569..1867415 (+)	847	Protein_1895	IS630 family transposase	-
R4707_RS09820	clpE	1867622..1869880 (-)	2259	WP_081543116.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
R4707_RS09825	-	1870109..1870339 (-)	231	WP_000443573.1	YkuJ family protein	-
R4707_RS09830	-	1870529..1871212 (+)	684	WP_001011637.1	amino acid ABC transporter permease	-
R4707_RS09835	-	1871212..1871946 (+)	735	WP_000140941.1	amino acid ABC transporter ATP-binding protein	-
R4707_RS09840	-	1872100..1872957 (+)	858	WP_000192078.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
R4707_RS09845	-	1873099..1873971 (+)	873	WP_000864671.1	NAD(P)H-hydrate dehydratase	-

Sequence

Protein

• Length: 752 a.a.
• Molecular weight: 83869.35 Da
• Isoelectric Point: 5.5494

>NTDB_id=820041 R4707_RS09820 WP_081543116.1 1867622..1869880(-) (clpE) [Streptococcus pneumoniae strain ZGX]
MLCQNCKINDSTIHLYTNINGKQKQIDLCQNCYKIIKTDPNNSLFKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPP
TQSGGGYGGNGGYGSQNRGSAQTPPPSQEKGLLKEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSA
SDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAA
IEAATTLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRDQIAKYKEM
QKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKSHVIGQDDAVDKIAKAIRRNRVGLGTPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELGNFFSPEFMNRF
DGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENP
SEKDLKAVMTSKGNIQIKSAKKAEVKSSEKEK

Nucleotide

• Length: 2259 bp

>NTDB_id=820041 R4707_RS09820 WP_081543116.1 1867622..1869880(-) (clpE) [Streptococcus pneumoniae strain ZGX]
ATGCTTTGTCAAAACTGTAAAATTAACGACTCAACAATTCATCTTTACACCAATATCAATGGAAAACAAAAACAAATTGA
CCTCTGTCAAAACTGCTATAAGATTATCAAAACAGATCCTAACAATAGCCTCTTCAAAGGTATGACGGATCTGAACAATC
GTGACTTCGATCCCTTTGGTGATTTCTTCAATGATCTAAACAATTTCAGACCTTCTAGCAATACTCCTCCTATTCCCCCA
ACCCAATCAGGTGGAGGTTACGGTGGAAACGGCGGTTATGGTTCCCAAAATCGTGGATCTGCTCAAACTCCGCCACCTAG
CCAAGAAAAAGGCCTGCTGAAAGAATTTGGTATTAATGTAACTGAAATTGCCCGTCGTGGAGACATTGACCCCGTTATTG
GGCGCGACGATGAGATTATCCGTGTCATCGAGATTCTCAATCGTAGAACCAAGAATAATCCTGTCCTTATCGGTGAACCT
GGTGTCGGAAAAACGGCCGTTGTCGAAGGTCTAGCTCAGAAAATTGTCGATGGCGATGTGCCACATAAACTCCAAGGTAA
ACAAGTCATCCGTCTGGATGTGGTTAGCTTAGTTCAAGGAACGGGGATTCGAGGACAATTTGAAGAACGCATGCAAAAAC
TCATGGAAGAAATTCGCAAACGTGAAGACATCATCCTCTTTATCGATGAAATCCATGAAATTGTTGGTGCTGGTTCTGCG
AGTGATGGTAATATGGACGCAGGAAATATCCTCAAGCCAGCCCTTGCTCGTGGAGAACTGCAACTAGTCGGTGCTACTAC
CCTCAATGAATACCGTATCATTGAAAAGGATGCTGCCCTCGAGCGTCGTATGCAGCCTGTTAAAGTCGATGAACCAACGG
TGGACGAAACAATCACTATTCTCAAAGGGATTCAAAAGAAATACGAAGATTACCACCACGTTCAATATACAGATGCTGCG
ATTGAAGCAGCTACAACTCTTTCCAATCGCTACATCCAAGATCGCTTCTTGCCTGACAAGGCCATTGACCTCCTAGATGA
AGCTGGTTCTAAGATGAACTTGACCTTGAATTTTGTGGATCCTAAAGTAATTGATCAGCGCTTGATTGAGGCTGAAAATC
TCAAGTCTCAAGCTACACGAGAAGAAGATTTTGAGAAGGCGGCCTACTTCCGCGACCAGATTGCCAAGTATAAGGAAATG
CAAAAGAAAAAGATCACAGACCAGGATACTCCTATCATCAGCGAGAAAACTATTGAGCACATTATCGAGCAGAAAACCAA
TATCCCTGTTGGTGATTTGAAAGAGAAAGAACAATCTCAACTCATCCATCTAGCCGAAGATCTCAAGTCTCATGTTATTG
GTCAAGATGATGCAGTCGATAAGATTGCCAAGGCTATTCGCCGTAATCGTGTCGGACTTGGTACCCCTAACCGCCCAATC
GGAAGCTTCCTCTTCGTTGGGCCAACTGGTGTCGGTAAGACAGAACTTTCCAAACAACTGGCTATCGAACTTTTTGGTTC
TGCTGATAGTATGATTCGCTTTGATATGAGTGAATACATGGAAAAACATAGTGTGGCTAAGTTGGTCGGCGCTCCTCCAG
GTTATGTTGGCTATGATGAGGCTGGTCAATTAACTGAAAAAGTTCGCCACAATCCATATTCTCTCATCCTTCTCGATGAA
GTGGAAAAAGCTCACCCAGATGTTATGCACATGTTTCTTCAAGTCTTGGACGATGGTCGTTTGACAGACGGGCAAGGACG
CACCGTTAGCTTCAAGGATGCCATCATTATCATGACCTCAAATGCAGGTACAGGAAAGACCGAAGCTAGCGTTGGATTTG
GTGCTGCTAGAGAAGGACGTACCAATTCTGTCCTCGGTGAACTCGGTAACTTCTTTAGCCCAGAGTTTATGAACCGTTTT
GATGGCATTATCGAATTTAAGGCTCTCAGCAAGGATAACCTCCTTCAGATTGTCGAGCTCATGCTAGCAGATGTTAACAA
GCGCCTCTCTAGCAACAACATTCGTTTGGATGTAACTGATAAGGTCAAGGAAAAGTTGGTTGACCTAGGTTATGATCCAA
AAATGGGAGCACGCCCACTTCGTCGGACTATTCAAGACTATATTGAGGACACAATCACTGACTACTACCTTGAAAATCCA
AGCGAAAAAGATCTCAAAGCAGTTATGACTAGCAAGGGAAACATTCAGATTAAATCTGCCAAAAAAGCTGAAGTTAAAAG
TTCTGAAAAAGAAAAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (649-723)

• AAA lid domain (AAA_lid_9) (293-390)

• ATPase family associated with various cellular activities (AAA) (AAA) (155-276)

• AAA domain (Cdc48 subfamily) (AAA_2) (478-641)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	99.601	100	0.996
clpE	Streptococcus pneumoniae D39	99.601	100	0.996
clpE	Streptococcus pneumoniae R6	99.601	100	0.996
clpE	Streptococcus pneumoniae TIGR4	99.468	100	0.995
clpE	Streptococcus mutans UA159	82.463	99.335	0.819
clpC	Lactococcus lactis subsp. cremoris KW2	76.567	97.606	0.747
clpC	Bacillus subtilis subsp. subtilis str. 168	52.308	86.436	0.452
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.987	82.58	0.396
clpC	Streptococcus pneumoniae Rx1	46.751	83.91	0.392
clpC	Streptococcus pneumoniae D39	46.751	83.91	0.392
clpC	Streptococcus pneumoniae TIGR4	46.751	83.91	0.392
clpC	Streptococcus thermophilus LMD-9	46.795	82.979	0.388
clpC	Streptococcus mutans UA159	46.571	83.378	0.388
clpC	Streptococcus thermophilus LMG 18311	46.4	83.112	0.386