Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   R4707_RS06745 Genome accession   NZ_CP137113
Coordinates   1259063..1259503 (-) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain ZGX     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1254063..1264503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4707_RS06720 - 1254324..1255562 (+) 1239 WP_317830783.1 response regulator transcription factor -
  R4707_RS06725 - 1255662..1256195 (+) 534 WP_000729030.1 hypothetical protein -
  R4707_RS06730 nrdI 1256273..1256743 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  R4707_RS06735 - 1257036..1258298 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  R4707_RS06740 - 1258608..1259066 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  R4707_RS06745 brsR 1259063..1259503 (-) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  R4707_RS06750 - 1259591..1259716 (-) 126 WP_001813544.1 hypothetical protein -
  R4707_RS06755 hexB 1259859..1261808 (+) 1950 WP_000018169.1 DNA mismatch repair endonuclease MutL Machinery gene
  R4707_RS06760 ribE 1262133..1262600 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  R4707_RS06765 - 1262601..1263806 (-) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  R4707_RS06770 ribE 1263826..1264461 (-) 636 WP_000493841.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=820014 R4707_RS06745 WP_000861956.1 1259063..1259503(-) (brsR) [Streptococcus pneumoniae strain ZGX]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=820014 R4707_RS06745 WP_000861956.1 1259063..1259503(-) (brsR) [Streptococcus pneumoniae strain ZGX]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363