Detailed information NTG0819927

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAY75_RS10305
• Genome accession: NZ_CP123168
• Coordinates: 2100451..2101338 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BE-MSSA4
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2095451..2106338

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY75_RS10275 (QAY75_10295)	-	2096183..2096944 (+)	762	WP_000323441.1	alpha/beta hydrolase	-
QAY75_RS10280 (QAY75_10300)	-	2097189..2097644 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAY75_RS10285 (QAY75_10305)	-	2097766..2097867 (+)	102	WP_000731976.1	SE2200 family small protein	-
QAY75_RS10290 (QAY75_10310)	-	2097927..2099351 (-)	1425	WP_000953755.1	alkaline phosphatase	-
QAY75_RS10295 (QAY75_10315)	-	2099549..2099749 (+)	201	WP_000604730.1	hypothetical protein	-
QAY75_RS10300 (QAY75_10320)	braR	2099775..2100440 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAY75_RS10305 (QAY75_10325)	braS	2100451..2101338 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAY75_RS10310 (QAY75_10330)	-	2101446..2102201 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QAY75_RS10315 (QAY75_10335)	-	2102198..2104198 (+)	2001	WP_000776751.1	ABC transporter permease	-
QAY75_RS10320 (QAY75_10340)	-	2104857..2104970 (+)	114	Protein_1996	hypothetical protein	-
QAY75_RS10325 (QAY75_10345)	-	2105352..2105612 (+)	261	WP_001791974.1	hypothetical protein	-
QAY75_RS10330 (QAY75_10350)	-	2105622..2106119 (+)	498	WP_001065268.1	glutathione peroxidase	-
QAY75_RS10335 (QAY75_10355)	-	2106227..2106319 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=819927 QAY75_RS10305 WP_000143425.1 2100451..2101338(+) (braS) [Staphylococcus aureus strain BE-MSSA4]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=819927 QAY75_RS10305 WP_000143425.1 2100451..2101338(+) (braS) [Staphylococcus aureus strain BE-MSSA4]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1