Detailed information NTG0819891

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QAY75_RS00470
• Genome accession: NZ_CP123168
• Coordinates: 82612..83655 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BE-MSSA4
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 77612..88655

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY75_RS00440 (QAY75_00440)	-	78038..78148 (+)	111	WP_001790257.1	hypothetical protein	-
QAY75_RS00445 (QAY75_00445)	-	78177..78590 (+)	414	WP_001557448.1	hypothetical protein	-
QAY75_RS00450 (QAY75_00450)	-	79021..80007 (-)	987	WP_000999717.1	FUSC family protein	-
QAY75_RS00455 (QAY75_00455)	map	80538..81296 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QAY75_RS00460 (QAY75_00460)	-	81513..81899 (+)	387	WP_001110179.1	hypothetical protein	-
QAY75_RS00465 (QAY75_00465)	liaF	81914..82615 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QAY75_RS00470 (QAY75_00470)	vraS	82612..83655 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QAY75_RS00475 (QAY75_00475)	vraR	83645..84274 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QAY75_RS00480 (QAY75_00480)	-	84387..85604 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
QAY75_RS00485 (QAY75_00485)	-	85882..86157 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
QAY75_RS00490 (QAY75_00490)	-	86164..86628 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QAY75_RS00495 (QAY75_00495)	-	86775..86975 (+)	201	WP_000180460.1	DUF1128 family protein	-
QAY75_RS00500 (QAY75_00500)	-	86978..88234 (+)	1257	WP_001795108.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=819891 QAY75_RS00470 WP_001017131.1 82612..83655(+) (vraS) [Staphylococcus aureus strain BE-MSSA4]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=819891 QAY75_RS00470 WP_001017131.1 82612..83655(+) (vraS) [Staphylococcus aureus strain BE-MSSA4]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1