Detailed information NTG0819841

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAO30_RS10130
• Genome accession: NZ_CP123164
• Coordinates: 2030189..2031076 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain BE-MSSA6
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2025189..2036076

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO30_RS10100 (QAO30_10090)	-	2025208..2025300 (+)	93	WP_010956583.1	hypothetical protein	-
QAO30_RS10105 (QAO30_10095)	-	2025408..2025905 (-)	498	WP_001065268.1	glutathione peroxidase	-
QAO30_RS10110 (QAO30_10100)	-	2025915..2026175 (-)	261	WP_001791974.1	hypothetical protein	-
QAO30_RS10115 (QAO30_10105)	-	2026557..2026670 (-)	114	Protein_1963	hypothetical protein	-
QAO30_RS10120 (QAO30_10110)	-	2027329..2029329 (-)	2001	WP_000776740.1	ABC transporter permease	-
QAO30_RS10125 (QAO30_10115)	-	2029326..2030081 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QAO30_RS10130 (QAO30_10120)	braS	2030189..2031076 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAO30_RS10135 (QAO30_10125)	braR	2031087..2031752 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAO30_RS10140 (QAO30_10130)	-	2031778..2031978 (-)	201	WP_000604727.1	hypothetical protein	-
QAO30_RS10145 (QAO30_10135)	-	2032176..2033600 (+)	1425	WP_000953748.1	alkaline phosphatase	-
QAO30_RS10150	-	2033660..2033761 (-)	102	WP_000731972.1	SE2200 family small protein	-
QAO30_RS10155 (QAO30_10145)	-	2033883..2034338 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAO30_RS10160 (QAO30_10150)	-	2034583..2035344 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=819841 QAO30_RS10130 WP_000143417.1 2030189..2031076(-) (braS) [Staphylococcus aureus strain BE-MSSA6]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=819841 QAO30_RS10130 WP_000143417.1 2030189..2031076(-) (braS) [Staphylococcus aureus strain BE-MSSA6]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99