Detailed information NTG0819836

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QAO30_RS06615
• Genome accession: NZ_CP123164
• Coordinates: 1338576..1339619 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BE-MSSA6
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1333576..1344619

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO30_RS06585 (QAO30_06580)	-	1333998..1335254 (-)	1257	WP_072419726.1	aminopeptidase	-
QAO30_RS06590 (QAO30_06585)	-	1335257..1335457 (-)	201	WP_000180460.1	DUF1128 family protein	-
QAO30_RS06595 (QAO30_06590)	-	1335604..1336068 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QAO30_RS06600 (QAO30_06595)	-	1336075..1336350 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QAO30_RS06605 (QAO30_06600)	-	1336628..1337845 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
QAO30_RS06610 (QAO30_06605)	vraR	1337957..1338586 (-)	630	WP_000153536.1	two-component system response regulator VraR	Regulator
QAO30_RS06615 (QAO30_06610)	vraS	1338576..1339619 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QAO30_RS06620 (QAO30_06615)	liaF	1339616..1340317 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QAO30_RS06625 (QAO30_06620)	-	1340332..1340718 (-)	387	WP_001110179.1	hypothetical protein	-
QAO30_RS06630 (QAO30_06625)	map	1340935..1341693 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QAO30_RS06635 (QAO30_06630)	-	1342224..1343210 (+)	987	WP_000999713.1	FUSC family protein	-
QAO30_RS06640 (QAO30_06635)	-	1343700..1344113 (-)	414	WP_001566709.1	hypothetical protein	-
QAO30_RS06645 (QAO30_06640)	-	1344142..1344252 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=819836 QAO30_RS06615 WP_001017131.1 1338576..1339619(-) (vraS) [Staphylococcus aureus strain BE-MSSA6]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=819836 QAO30_RS06615 WP_001017131.1 1338576..1339619(-) (vraS) [Staphylococcus aureus strain BE-MSSA6]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGCATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1