Detailed information NTG0819800

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QAY77_RS09365
• Genome accession: NZ_CP123162
• Coordinates: 1912689..1913732 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BE-MSSA7
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1907689..1918732

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY77_RS09335 (QAY77_09330)	-	1908107..1909363 (-)	1257	WP_411888668.1	aminopeptidase	-
QAY77_RS09340 (QAY77_09335)	-	1909366..1909566 (-)	201	WP_000180461.1	DUF1128 family protein	-
QAY77_RS09345 (QAY77_09340)	-	1909713..1910177 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QAY77_RS09350 (QAY77_09345)	-	1910184..1910459 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QAY77_RS09355 (QAY77_09350)	-	1910737..1911954 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
QAY77_RS09360 (QAY77_09355)	vraR	1912070..1912699 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
QAY77_RS09365 (QAY77_09360)	vraS	1912689..1913732 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QAY77_RS09370 (QAY77_09365)	liaF	1913729..1914430 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QAY77_RS09375 (QAY77_09370)	-	1914445..1914831 (-)	387	WP_001110179.1	hypothetical protein	-
QAY77_RS09380 (QAY77_09375)	map	1915048..1915806 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QAY77_RS09385 (QAY77_09380)	-	1916393..1917379 (+)	987	WP_000999713.1	FUSC family protein	-
QAY77_RS09390 (QAY77_09385)	-	1917810..1918223 (-)	414	WP_001549145.1	hypothetical protein	-
QAY77_RS09395 (QAY77_09390)	-	1918252..1918362 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=819800 QAY77_RS09365 WP_001017131.1 1912689..1913732(-) (vraS) [Staphylococcus aureus strain BE-MSSA7]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=819800 QAY77_RS09365 WP_001017131.1 1912689..1913732(-) (vraS) [Staphylococcus aureus strain BE-MSSA7]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1