Detailed information NTG0819760

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QAY67_RS09965
• Genome accession: NZ_CP123160
• Coordinates: 2033054..2034097 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BE-MSSA8
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2028054..2039097

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY67_RS09935 (QAY67_09960)	-	2028476..2029732 (-)	1257	WP_072419726.1	aminopeptidase	-
QAY67_RS09940 (QAY67_09965)	-	2029735..2029935 (-)	201	WP_000180460.1	DUF1128 family protein	-
QAY67_RS09945 (QAY67_09970)	-	2030082..2030546 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QAY67_RS09950 (QAY67_09975)	-	2030553..2030828 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QAY67_RS09955 (QAY67_09980)	-	2031106..2032323 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
QAY67_RS09960 (QAY67_09985)	vraR	2032435..2033064 (-)	630	WP_000153536.1	two-component system response regulator VraR	Regulator
QAY67_RS09965 (QAY67_09990)	vraS	2033054..2034097 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QAY67_RS09970 (QAY67_09995)	liaF	2034094..2034795 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QAY67_RS09975 (QAY67_10000)	-	2034810..2035196 (-)	387	WP_001110179.1	hypothetical protein	-
QAY67_RS09980 (QAY67_10005)	map	2035413..2036171 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QAY67_RS09985 (QAY67_10010)	-	2036587..2037573 (+)	987	WP_000999713.1	FUSC family protein	-
QAY67_RS09990 (QAY67_10015)	-	2038063..2038476 (-)	414	WP_001566709.1	hypothetical protein	-
QAY67_RS09995 (QAY67_10020)	-	2038505..2038615 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=819760 QAY67_RS09965 WP_001017131.1 2033054..2034097(-) (vraS) [Staphylococcus aureus strain BE-MSSA8]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=819760 QAY67_RS09965 WP_001017131.1 2033054..2034097(-) (vraS) [Staphylococcus aureus strain BE-MSSA8]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGCATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1