Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   R4706_RS03720 Genome accession   NZ_CP137111
Coordinates   758844..760949 (-) Length   701 a.a.
NCBI ID   WP_044727934.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 17023     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 753844..765949
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4706_RS03695 - 753851..754018 (-) 168 WP_033607495.1 S-ribosylhomocysteinase -
  R4706_RS03700 - 754183..755790 (-) 1608 WP_001156834.1 alpha-glucosidase -
  R4706_RS03705 - 755943..757427 (+) 1485 WP_000743596.1 DUF1846 domain-containing protein -
  R4706_RS03710 - 757522..758004 (+) 483 WP_000032550.1 S-ribosylhomocysteine lyase -
  R4706_RS03715 - 758071..758406 (-) 336 Protein_736 group II intron maturase-specific domain-containing protein -
  R4706_RS03720 clpC 758844..760949 (-) 2106 WP_044727934.1 AAA family ATPase Regulator
  R4706_RS03725 mraY 761558..762538 (-) 981 WP_000470785.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
  R4706_RS03730 pbp2X 762540..764792 (-) 2253 WP_050198602.1 penicillin-binding protein 2X -
  R4706_RS03735 ftsL 764796..765113 (-) 318 WP_000818547.1 cell division protein FtsL -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77581.38 Da        Isoelectric Point: 4.7036

>NTDB_id=819733 R4706_RS03720 WP_044727934.1 758844..760949(-) (clpC) [Streptococcus pneumoniae strain 17023]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQYHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMKDGVLVIREKA

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=819733 R4706_RS03720 WP_044727934.1 758844..760949(-) (clpC) [Streptococcus pneumoniae strain 17023]
ATGAATAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAATCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGCCGTTACTTAATTAATGGACGCGAAGTCACACCTGAGGAATTTGCTCACTATCGTGCGACTGGTCAATTAC
CAGGAAATGCAGAAACTGATGTGCAAATGCCACAACAGGCATCAGGTATGAAACAAGACGGTGTCCTTGCAAAACTAGGT
CGAAACTTAACAGCAGAAGCGCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGCCGCACCAAGAACAATCCTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCAGTTGTCGAAGGTC
TAGCGCAAGCCATTGTGAACGGAGATGTTCCTGCTGCTATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGGCTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTAACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCGGCAGAGAATACTTTTAAAATTCT
TCAAGGAATTCGTGACCTCTATCAACAATACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACAGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGCTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAGCTTCCTCTTTGTAGGGTCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGATCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACAATTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACATTGGCTAAGAAAGACATTGACTTGGTAGTCAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGCGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGAAAGATGGCG
TTTTGGTTATTCGTGAGAAAGCCTAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(259-354)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

50.234

91.441

0.459
  clpE Streptococcus mutans UA159

49.377

91.583

0.452
  clpE Streptococcus pneumoniae TIGR4

48.107

90.442

0.435
  clpE Streptococcus pneumoniae Rx1

48.107

90.442

0.435
  clpE Streptococcus pneumoniae D39

48.107

90.442

0.435
  clpE Streptococcus pneumoniae R6

48.107

90.442

0.435
  clpC Bacillus subtilis subsp. subtilis str. 168

44.53

92.582

0.412
  clpC Streptococcus thermophilus LMD-9

42.654

90.3

0.385
  clpC Streptococcus pneumoniae Rx1

42.496

90.3

0.384
  clpC Streptococcus pneumoniae D39

42.496

90.3

0.384
  clpC Streptococcus thermophilus LMG 18311

42.496

90.3

0.384
  clpC Streptococcus pneumoniae TIGR4

42.338

90.3

0.382
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.274

88.017

0.381
  clpC Streptococcus mutans UA159

42.071

88.16

0.371