Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   R4706_RS00415 Genome accession   NZ_CP137111
Coordinates   87753..88217 (-) Length   154 a.a.
NCBI ID   WP_001135782.1    Uniprot ID   P59659
Organism   Streptococcus pneumoniae strain 17023     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 82753..93217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4706_RS00395 - 83704..84672 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  R4706_RS00400 pdrM 84826..86187 (-) 1362 WP_000278539.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  R4706_RS00405 - 86198..86458 (-) 261 WP_001105925.1 hypothetical protein -
  R4706_RS00410 - 86472..87740 (-) 1269 WP_000924482.1 dihydroorotase -
  R4706_RS00415 mutX 87753..88217 (-) 465 WP_001135782.1 8-oxo-dGTP diphosphatase Machinery gene
  R4706_RS00420 - 88227..88880 (-) 654 WP_000401328.1 uracil-DNA glycosylase -
  R4706_RS00425 - 89016..89618 (-) 603 WP_001810555.1 hypothetical protein -
  R4706_RS00430 - 89676..90389 (-) 714 WP_000499431.1 YjjG family noncanonical pyrimidine nucleotidase -
  R4706_RS00435 dhaM 90848..91228 (-) 381 WP_000443784.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  R4706_RS00440 - 91228..91302 (-) 75 Protein_87 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17870.30 Da        Isoelectric Point: 4.2287

>NTDB_id=819699 R4706_RS00415 WP_001135782.1 87753..88217(-) (mutX) [Streptococcus pneumoniae strain 17023]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAVREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGMLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=819699 R4706_RS00415 WP_001135782.1 87753..88217(-) (mutX) [Streptococcus pneumoniae strain 17023]
ATGCCTCAGTTAGCGACGATTTGTTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGTACGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGATGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P59659

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

100

100

1