Detailed information NTG0819686

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QAO39_RS03575
• Genome accession: NZ_CP123158
• Coordinates: 707384..708427 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BE-MSSA9
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 702384..713427

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO39_RS03545 (QAO39_03545)	-	702751..702861 (+)	111	WP_001790257.1	hypothetical protein	-
QAO39_RS03550 (QAO39_03550)	-	702890..703303 (+)	414	WP_001670387.1	hypothetical protein	-
QAO39_RS03555 (QAO39_03555)	-	703734..704720 (-)	987	WP_000999713.1	FUSC family protein	-
QAO39_RS03560 (QAO39_03560)	map	705310..706068 (+)	759	WP_411896659.1	type I methionyl aminopeptidase	-
QAO39_RS03565 (QAO39_03565)	-	706285..706671 (+)	387	WP_001110179.1	hypothetical protein	-
QAO39_RS03570 (QAO39_03570)	liaF	706686..707387 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QAO39_RS03575 (QAO39_03575)	vraS	707384..708427 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QAO39_RS03580 (QAO39_03580)	vraR	708417..709046 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QAO39_RS03585 (QAO39_03585)	-	709158..710375 (-)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
QAO39_RS03590 (QAO39_03590)	-	710653..710928 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
QAO39_RS03595 (QAO39_03595)	-	710935..711399 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QAO39_RS03600 (QAO39_03600)	-	711546..711746 (+)	201	WP_000180460.1	DUF1128 family protein	-
QAO39_RS03605 (QAO39_03605)	-	711749..713005 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=819686 QAO39_RS03575 WP_001017131.1 707384..708427(+) (vraS) [Staphylococcus aureus strain BE-MSSA9]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=819686 QAO39_RS03575 WP_001017131.1 707384..708427(+) (vraS) [Staphylococcus aureus strain BE-MSSA9]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1