Detailed information NTG0819633

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QAY79_RS09785
• Genome accession: NZ_CP123154
• Coordinates: 2018671..2019714 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain GE-MRSA17
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2013671..2024714

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY79_RS09755 (QAY79_09785)	-	2014092..2015348 (-)	1257	WP_001795108.1	aminopeptidase	-
QAY79_RS09760 (QAY79_09790)	-	2015351..2015551 (-)	201	WP_000180460.1	DUF1128 family protein	-
QAY79_RS09765 (QAY79_09795)	-	2015698..2016162 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QAY79_RS09770 (QAY79_09800)	-	2016169..2016444 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QAY79_RS09775 (QAY79_09805)	-	2016722..2017939 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
QAY79_RS09780 (QAY79_09810)	vraR	2018052..2018681 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QAY79_RS09785 (QAY79_09815)	vraS	2018671..2019714 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QAY79_RS09790 (QAY79_09820)	liaF	2019711..2020412 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QAY79_RS09795 (QAY79_09825)	-	2020427..2020813 (-)	387	WP_001110179.1	hypothetical protein	-
QAY79_RS09800 (QAY79_09830)	map	2021030..2021788 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QAY79_RS09805 (QAY79_09835)	-	2022319..2023305 (+)	987	WP_000999717.1	FUSC family protein	-
QAY79_RS09810 (QAY79_09840)	-	2023736..2024149 (-)	414	WP_001557448.1	hypothetical protein	-
QAY79_RS09815 (QAY79_09845)	-	2024178..2024288 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=819633 QAY79_RS09785 WP_001017131.1 2018671..2019714(-) (vraS) [Staphylococcus aureus strain GE-MRSA17]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=819633 QAY79_RS09785 WP_001017131.1 2018671..2019714(-) (vraS) [Staphylococcus aureus strain GE-MRSA17]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1