Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   R4712_RS03635 Genome accession   NZ_CP137110
Coordinates   736922..739027 (-) Length   701 a.a.
NCBI ID   WP_044812856.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2041     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 731922..744027
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4712_RS03620 - 732803..734413 (-) 1611 WP_044812601.1 alpha-glucosidase -
  R4712_RS03625 - 734566..736050 (+) 1485 WP_000743612.1 DUF1846 domain-containing protein -
  R4712_RS03630 - 736145..736627 (+) 483 WP_000032550.1 S-ribosylhomocysteine lyase -
  R4712_RS03635 clpC 736922..739027 (-) 2106 WP_044812856.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  R4712_RS03640 mraY 739591..740571 (-) 981 WP_000470858.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
  R4712_RS03645 pbp2X 740573..742825 (-) 2253 WP_044812287.1 penicillin-binding protein 2X -
  R4712_RS03650 ftsL 742829..743146 (-) 318 WP_000818547.1 cell division protein FtsL -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77581.34 Da        Isoelectric Point: 4.7080

>NTDB_id=819610 R4712_RS03635 WP_044812856.1 736922..739027(-) (clpC) [Streptococcus pneumoniae strain 16H2041]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHLVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=819610 R4712_RS03635 WP_044812856.1 736922..739027(-) (clpC) [Streptococcus pneumoniae strain 16H2041]
ATGAATAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGCCGTTACTTAATTAATGGACGCGAAGTCACACCTGAGGAATTTGCTCACTATCGTGCGACTGGTCAATTAC
CAGGAAATGCAGAAACTGATGTGCAAATGCCACAACAGGCATCAGGTATGAAACAAGACGGTGTCCTTGCAAAACTAGGT
CGAAACTTAACAGCAGAAGCGCGTGAGGGCAAGTTGGACCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGCCGCACCAAGAACAATCCTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCAGTTGTCGAAGGTC
TAGCGCAAGCCATTGTGAACGGAGATGTTCCTGCTGCTATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGACTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCAGCAGAGAATACTTTTAAAATTCT
TCAAGGCATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACGGCGGCTCACTTGGCGGCT
CAACATCTAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAATGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCCCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGCTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAGCTTCCTCTTTGTAGGGTCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGTACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGACCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACACTTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTTAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGAGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAGAAAGCCTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA lid domain (AAA_lid_9)

(259-354)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

50.078

91.441

0.458
  clpE Streptococcus mutans UA159

49.221

91.583

0.451
  clpE Streptococcus pneumoniae TIGR4

47.95

90.442

0.434
  clpE Streptococcus pneumoniae Rx1

47.95

90.442

0.434
  clpE Streptococcus pneumoniae D39

47.95

90.442

0.434
  clpE Streptococcus pneumoniae R6

47.95

90.442

0.434
  clpC Bacillus subtilis subsp. subtilis str. 168

44.838

92.582

0.415
  clpC Streptococcus pneumoniae Rx1

42.654

90.3

0.385
  clpC Streptococcus pneumoniae D39

42.654

90.3

0.385
  clpC Streptococcus pneumoniae TIGR4

42.496

90.3

0.384
  clpC Streptococcus thermophilus LMD-9

42.496

90.3

0.384
  clpC Streptococcus thermophilus LMG 18311

42.338

90.3

0.382
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.112

88.017

0.379
  clpC Streptococcus mutans UA159

42.742

88.445

0.378