Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   R8613_RS05700 Genome accession   NZ_AP026919
Coordinates   1098814..1099278 (-) Length   154 a.a.
NCBI ID   WP_001135782.1    Uniprot ID   P59659
Organism   Streptococcus pneumoniae strain PZ900700012     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1093814..1104278
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8613_RS05680 (PC0012_10990) - 1094765..1095733 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  R8613_RS05685 (PC0012_11000) pdrM 1095887..1097248 (-) 1362 WP_050201201.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  R8613_RS05690 (PC0012_11010) - 1097259..1097519 (-) 261 WP_001105925.1 hypothetical protein -
  R8613_RS05695 (PC0012_11020) - 1097533..1098801 (-) 1269 WP_000924481.1 dihydroorotase -
  R8613_RS05700 (PC0012_11030) mutX 1098814..1099278 (-) 465 WP_001135782.1 8-oxo-dGTP diphosphatase Machinery gene
  R8613_RS05705 (PC0012_11040) - 1099288..1099941 (-) 654 WP_000401328.1 uracil-DNA glycosylase -
  R8613_RS05710 (PC0012_11050) - 1100077..1100679 (-) 603 WP_001810555.1 hypothetical protein -
  R8613_RS05715 (PC0012_11060) - 1100737..1101450 (-) 714 WP_000499431.1 YjjG family noncanonical pyrimidine nucleotidase -
  R8613_RS05720 (PC0012_11070) dhaM 1101909..1102289 (-) 381 WP_000443784.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  R8613_RS05725 - 1102289..1102363 (-) 75 Protein_1137 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17870.30 Da        Isoelectric Point: 4.2287

>NTDB_id=81954 R8613_RS05700 WP_001135782.1 1098814..1099278(-) (mutX) [Streptococcus pneumoniae strain PZ900700012]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAVREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGMLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=81954 R8613_RS05700 WP_001135782.1 1098814..1099278(-) (mutX) [Streptococcus pneumoniae strain PZ900700012]
ATGCCTCAGTTAGCGACGATTTGTTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGTACGTGAAA
TCCTTGAAGAAACAGGACTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGATGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P59659

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

100

100

1

Multiple sequence alignment