Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   R4704_RS00320 Genome accession   NZ_CP137109
Coordinates   61998..62462 (-) Length   154 a.a.
NCBI ID   WP_001135782.1    Uniprot ID   P59659
Organism   Streptococcus pneumoniae strain 11012     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 56998..67462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4704_RS00300 - 57949..58917 (-) 969 WP_033705551.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  R4704_RS00305 pdrM 59071..60432 (-) 1362 WP_317830420.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  R4704_RS00310 - 60443..60703 (-) 261 WP_001105925.1 hypothetical protein -
  R4704_RS00315 - 60717..61985 (-) 1269 WP_033705552.1 dihydroorotase -
  R4704_RS00320 mutX 61998..62462 (-) 465 WP_001135782.1 8-oxo-dGTP diphosphatase Machinery gene
  R4704_RS00325 - 62472..63125 (-) 654 WP_000401328.1 uracil-DNA glycosylase -
  R4704_RS00330 - 63261..63908 (-) 648 WP_050456368.1 hypothetical protein -
  R4704_RS00335 - 63922..64635 (-) 714 WP_033705553.1 YjjG family noncanonical pyrimidine nucleotidase -
  R4704_RS00340 dhaM 65094..65474 (-) 381 WP_033705554.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  R4704_RS11130 - 65474..65548 (-) 75 Protein_68 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17870.30 Da        Isoelectric Point: 4.2287

>NTDB_id=819456 R4704_RS00320 WP_001135782.1 61998..62462(-) (mutX) [Streptococcus pneumoniae strain 11012]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAVREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGMLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=819456 R4704_RS00320 WP_001135782.1 61998..62462(-) (mutX) [Streptococcus pneumoniae strain 11012]
ATGCCTCAGTTAGCGACGATTTGTTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGTACGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGATGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACCTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P59659

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

100

100

1