Detailed information NTG0819332

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAO17_RS10645
• Genome accession: NZ_CP123134
• Coordinates: 2162493..2163380 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GE-MRSA25
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2157493..2168380

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO17_RS10615 (QAO17_10595)	-	2158224..2158985 (+)	762	WP_000323451.1	alpha/beta hydrolase	-
QAO17_RS10620 (QAO17_10600)	-	2159231..2159686 (+)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAO17_RS10625 (QAO17_10605)	-	2159808..2159909 (+)	102	WP_000731972.1	SE2200 family small protein	-
QAO17_RS10630 (QAO17_10610)	-	2159969..2161393 (-)	1425	WP_000953731.1	alkaline phosphatase	-
QAO17_RS10635 (QAO17_10615)	-	2161591..2161791 (+)	201	WP_000604723.1	hypothetical protein	-
QAO17_RS10640 (QAO17_10620)	braR	2161817..2162482 (+)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAO17_RS10645 (QAO17_10625)	braS	2162493..2163380 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAO17_RS10650 (QAO17_10630)	-	2163488..2164243 (+)	756	WP_000923771.1	ABC transporter ATP-binding protein	-
QAO17_RS10655 (QAO17_10635)	-	2164240..2166240 (+)	2001	WP_052995994.1	FtsX-like permease family protein	-
QAO17_RS10660 (QAO17_10640)	-	2166904..2167017 (+)	114	WP_072384844.1	hypothetical protein	-
QAO17_RS10665 (QAO17_10645)	-	2167399..2167659 (+)	261	WP_072434822.1	hypothetical protein	-
QAO17_RS10670 (QAO17_10650)	-	2167669..2168166 (+)	498	WP_001065267.1	glutathione peroxidase	-
QAO17_RS10675 (QAO17_10655)	-	2168274..2168362 (-)	89	Protein_2069	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=819332 QAO17_RS10645 WP_000143420.1 2162493..2163380(+) (braS) [Staphylococcus aureus strain GE-MRSA25]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=819332 QAO17_RS10645 WP_000143420.1 2162493..2163380(+) (braS) [Staphylococcus aureus strain GE-MRSA25]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993