Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QAY72_RS13345 Genome accession   NZ_CP123132
Coordinates   2707485..2708201 (-) Length   238 a.a.
NCBI ID   WP_083009669.1    Uniprot ID   -
Organism   Staphylococcus aureus strain GE-MSSA28     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2702485..2713201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAY72_RS13325 (QAY72_13330) - 2703579..2704529 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  QAY72_RS13330 (QAY72_13335) - 2704678..2706162 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  QAY72_RS13335 (QAY72_13340) - 2706159..2707118 (+) 960 WP_001253312.1 carbohydrate kinase family protein -
  QAY72_RS13340 (QAY72_13345) - 2707306..2707413 (-) 108 WP_001790167.1 hypothetical protein -
  QAY72_RS13345 (QAY72_13350) agrA 2707485..2708201 (-) 717 WP_083009669.1 quorum-sensing response regulator AgrA Regulator
  QAY72_RS13350 (QAY72_13355) agrC 2708220..2709512 (-) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  QAY72_RS13355 (QAY72_13360) agrD 2709537..2709677 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  QAY72_RS13360 (QAY72_13365) agrB 2709674..2710243 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  QAY72_RS13365 (QAY72_13370) hld 2710533..2710613 (+) 81 WP_000046022.1 delta-hemolysin -
  QAY72_RS13370 (QAY72_13375) - 2711210..2711995 (-) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  QAY72_RS13375 (QAY72_13380) - 2712356..2712982 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27949.91 Da        Isoelectric Point: 5.8625

>NTDB_id=819293 QAY72_RS13345 WP_083009669.1 2707485..2708201(-) (agrA) [Staphylococcus aureus strain GE-MSSA28]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQDKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=819293 QAY72_RS13345 WP_083009669.1 2707485..2708201(-) (agrA) [Staphylococcus aureus strain GE-MSSA28]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGATAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996