Detailed information NTG0819259

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: R4711_RS04400
• Genome accession: NZ_CP137107
• Coordinates: 877171..880002 (-)
• Length: 943 a.a.
• NCBI ID: WP_001152899.1
• Uniprot ID: P63384
• Organism: Streptococcus pneumoniae strain 15H4024
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 872171..885002

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4711_RS04365	-	872299..873549 (-)	1251	WP_000464336.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
R4711_RS04370	-	873855..874160 (-)	306	WP_000017620.1	DUF1292 domain-containing protein	-
R4711_RS04375	ruvX	874176..874595 (-)	420	WP_001808830.1	Holliday junction resolvase RuvX	-
R4711_RS04380	-	874599..874865 (-)	267	WP_000507059.1	IreB family regulatory phosphoprotein	-
R4711_RS04385	-	874952..875521 (-)	570	WP_000725141.1	SP0191 family lipoprotein	-
R4711_RS04390	spx	875587..875985 (-)	399	WP_000591165.1	transcriptional regulator Spx	-
R4711_RS04395	-	876117..877178 (-)	1062	WP_001042856.1	Xaa-Pro peptidase family protein	-
R4711_RS04400	uvrA	877171..880002 (-)	2832	WP_001152899.1	excinuclease ABC subunit UvrA	Machinery gene
R4711_RS04405	-	880134..881078 (+)	945	WP_000815629.1	magnesium transporter CorA family protein	-
R4711_RS04410	-	881090..881773 (+)	684	WP_000078024.1	DUF1129 domain-containing protein	-
R4711_RS04415	-	882028..883059 (+)	1032	WP_000255084.1	S66 peptidase family protein	-
R4711_RS04420	-	883196..883873 (-)	678	WP_000987422.1	CPBP family intramembrane glutamic endopeptidase	-
R4711_RS04425	-	883870..884433 (-)	564	WP_000166586.1	DNA-3-methyladenine glycosylase I	-

Sequence

Protein

• Length: 943 a.a.
• Molecular weight: 104185.31 Da
• Isoelectric Point: 6.3544

>NTDB_id=819259 R4711_RS04400 WP_001152899.1 877171..880002(-) (uvrA) [Streptococcus pneumoniae strain 15H4024]
MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGL
SPAISIDQKTTSKNPRSTVGTTTEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRLFDSIEAALRIAEGYVIIDTMDD
SELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNML
EQAMKVFGVAMDKPFEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYTRTQMRLYM
NELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTLSENEAIIARPILKEIKDRLTFLNNVGLNYL
TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLI
DVGPGAGVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNLQNVTARFPLGKFIAVT
GVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHVDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVEFF
QHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIARLLKVLARFVD
DGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIIVTGTPEEVAANEASYTGHYLKGKLHHE

Nucleotide

• Length: 2832 bp

>NTDB_id=819259 R4711_RS04400 WP_001152899.1 877171..880002(-) (uvrA) [Streptococcus pneumoniae strain 15H4024]
ATGCAAGATAAAATTGTCATTCATGGGGCGCGTGCCCATAATTTAAAAAATATTGATGTGGAGATTCCGCGAGACAAGTT
GGTTGTCGTGACTGGCTTGTCAGGTTCAGGGAAGTCCAGTCTGGCTTTTGATACTCTCTATGCGGAGGGACAACGTCGCT
ATGTAGAGAGTTTGTCCGCCTACGCTCGTCAGTTCTTGGGAAATATGGAAAAACCAGATGTAGATGCCATTGATGGTCTC
AGCCCAGCTATTTCCATCGACCAGAAAACGACTAGTAAAAATCCTCGCTCGACGGTGGGAACGACGACTGAAATCAATGA
CTATCTGCGTCTCCTCTACGCACGTGTGGGGACGCCTTACTGTATCAACGGACATGGAGCTATCAATGCTTCTTCTGTGG
AGCAAATCGTTGATAAGGTTTTGGAGTTACCTGAACGCCAGCGCTTGCAGATCTTGGCTCCTGTCATCCGCAAGAAAAAA
GGCCAACATAAGAGTGTTATCGAGAAGGTTCAGAAAGACGGGTATGTTCGTGTCCGTGTGGATGGGGAAGTCTATGATGT
GACCGAAGTGCCAGAGTTGTCTAAGAGCAAGCAACACAATATCGATGTCGTGGTTGACCGTATTGTTATCAAGGAGGGCA
TTCGTAGTCGTCTCTTTGATTCCATTGAGGCTGCCCTTCGTATTGCAGAAGGTTATGTCATTATCGACACCATGGACGAC
TCGGAGTTGTTGTTCTCTGAGCATTATGCCTGTCCAGTTTGTGGTTTTACTGTCCCAGAGTTAGAGCCTCGTCTCTTTTC
TTTCAATGCTCCTTTTGGCTCTTGTAGTGAGTGTGACGGCTTGGGCATCAAGCTGGAGGTGGATACTGATTTGGTAGTGC
CAGATGCTAGCAAAACCTTACGTGAGGGAGCGCTAGCACCTTGGAATCCTATCTCATCCAACTACTATCCAAACATGTTA
GAGCAGGCCATGAAAGTCTTTGGAGTGGCTATGGATAAGCCTTTTGAGGACCTGTCAGAAGAAGATAAGAACTTGATTCT
CTATGGGTCAGATGGTAAGGAATTCCATTTCCACTATGAGAATGAATTTGGTGGCGTGCGCGATATCGACATTCCGTTTG
AGGGAGTTATCAATAATATCAAACGTCGTTACCATGAAACCAATAGCGATTACACTCGCACTCAGATGCGTCTCTACATG
AATGAGCTGACCTGCGGAACCTGTCAAGGCTATCGTCTCAATGACCAGGCCTTGTCTGTCCGTGTGGGCGGCCAGCAAGG
GCCACATATTGGAGAAATCTCAGACCTGTCTATCGCTGACCACTTGGACTTGGTGAGCCAGTTAACTTTGTCTGAAAATG
AAGCCATCATTGCTCGTCCCATTCTCAAGGAAATCAAGGATCGTTTGACCTTCCTTAATAATGTGGGTCTTAACTATCTA
ACCCTGTCACGTTCAGCAGGAACCCTTTCAGGTGGGGAAAGTCAGCGCATTCGTTTGGCAACCCAGATTGGTTCCAACCT
ATCAGGTGTCCTCTATATCCTAGACGAGCCGTCAATCGGTCTTCACCAGAGGGACAATGATCGCCTGATTGCCAGTCTGA
AAAAGATGCGTGACTTGGGCAATACTCTTATCGTGGTGGAACACGACGAAGATACCATGCGTGAGGCTGATTATCTGATT
GACGTTGGTCCTGGTGCCGGTGTTTTTGGTGGTGAGATTGTTGCAGCAGGTACACCTAAGCAAGTGGCTCGCAACAGCAA
GTCTATCACAGGTCAGTACTTGTCAGGCAAACGTGTCATCCCAGTACCAGAAGAGCGCCGTGTCGGAAATGGTCGTTTTA
TTGAAGTGATAGGAGCGCGTGAGAACAACTTGCAAAATGTCACGGCTCGCTTTCCACTAGGAAAATTTATCGCAGTGACA
GGTGTGTCGGGTTCAGGGAAATCGACTCTAATCAACAGCATTCTCAAAAAAGCCATTGCCCAGAAGCTCAACCGTAATTC
AGACAAACCTGGTAAGTTTAAGACTATTACAGGGATTGAGCATGTCGACCGTTTGATTGATATTGACCAGAGCCCTATCG
GACGGACGCCGAGGTCTAACCCAGCTACCTATACAGGAGTTTTTGACGATATACGTGACCTTTTTGCTCAGACAAATGAA
GCCAAGATTCGAGGCTACAAGAAGGGGCGCTTCAGTTTCAACGTCAAGGGAGGTCGCTGTGAAGCTTGCTCAGGTGACGG
GATTATCAAGATTGAGATGCACTTCTTGCCAGATGTTTATGTGGCTTGTGAAGTTTGCCACGGAACCCGCTATAACAGTG
AAACCCTAGAAGTTCACTACAAGGAAAAGAATATTTCGCAGGTCTTGGATATGACGGTCAACGATGCGGTAGAATTTTTC
CAACACATTCCGAAAATTCAACGCAAACTCCAGACCATCAAGGATGTAGGGCTAGGCTATGTGACCTTGGGACAGCCAGC
TACCACCCTTTCTGGGGGAGAAGCCCAACGTATGAAGTTAGCTAGCGAACTCCACAAACGATCGACAGGAAAATCTTTCT
ACATTCTGGATGAGCCGACGACAGGGCTTCATACAGAGGACATTGCTCGCCTGCTCAAGGTTTTAGCTCGCTTTGTAGAC
GATGGCAATACAGTCCTCGTCATCGAGCACAATCTGGATGTTATCAAGACGGCAGACCATATCATTGACTTGGGACCTGA
GGGCGGTGTCGGTGGTGGAACCATCATCGTAACAGGAACTCCAGAAGAAGTAGCTGCCAACGAAGCCAGCTATACAGGAC
ACTATTTGAAAGGAAAGTTACATCATGAATAA

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (132-238)

• ABC transporter (ABC_tran) (624-860)

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

3D structure

• AlphaFold DB: P63384

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	100	100	1
uvrA	Streptococcus pneumoniae TIGR4	100	100	1
uvrA	Streptococcus pneumoniae D39	100	100	1