Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   R4711_RS03755 Genome accession   NZ_CP137107
Coordinates   756450..758555 (-) Length   701 a.a.
NCBI ID   WP_281057544.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15H4024     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 751450..763555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4711_RS03740 - 752330..753940 (-) 1611 WP_281057545.1 alpha-glucosidase -
  R4711_RS03745 - 754093..755577 (+) 1485 WP_000743574.1 DUF1846 domain-containing protein -
  R4711_RS03750 - 755672..756154 (+) 483 WP_000032550.1 S-ribosylhomocysteine lyase -
  R4711_RS03755 clpC 756450..758555 (-) 2106 WP_281057544.1 AAA family ATPase Regulator
  R4711_RS03760 mraY 759164..760144 (-) 981 WP_033705613.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
  R4711_RS03765 pbp2X 760146..762398 (-) 2253 WP_033705614.1 penicillin-binding protein 2X -
  R4711_RS03770 ftsL 762402..762719 (-) 318 WP_000818547.1 cell division protein FtsL -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77395.20 Da        Isoelectric Point: 4.6779

>NTDB_id=819256 R4711_RS03755 WP_281057544.1 756450..758555(-) (clpC) [Streptococcus pneumoniae strain 15H4024]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQGKVIGQDKAVEAVACAIRRNRAGFDEGNRPIGSFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRCNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPELLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKV

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=819256 R4711_RS03755 WP_281057544.1 756450..758555(-) (clpC) [Streptococcus pneumoniae strain 15H4024]
ATGAATAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGCCGTTACTTAATTAATGGGCGCGAAGTCACACCTGAGGAATTTGCTCACTATCGTGCGACTGGTCAATTAC
CAGGAAATGCAGAAACTGATGTGCAAATGCCACAACAGGCATCAGGTATGAAACAAGACGGTGTCCTTGCAAAACTAGGT
CGAAACTTGACAGCAGAAGCGCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGCCGCACCAAGAACAATCCTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCAGTTGTCGAAGGTC
TAGCGCAAGCCATTGTGAACGGAGATGTTCCTGCTGCTATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGGCTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCGGCAGAGAATACTTTTAAAATTCT
TCAAGGAATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACAGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCCCATCGCTTGCAAGGCAAGGTGATTGGTCAAGATAAGGCCGTAGAAGCTGT
AGCTTGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAGCTTCCTCTTTGTAGGGTCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGTACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTTGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGATCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCTTTCTTCCGTCCAGAACTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACACTTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTCAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGCGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAGAAAGTCTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)

AAA lid domain (AAA_lid_9)

(259-354)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

49.766

91.441

0.455
  clpE Streptococcus mutans UA159

48.91

91.583

0.448
  clpE Streptococcus pneumoniae TIGR4

47.792

90.442

0.432
  clpE Streptococcus pneumoniae Rx1

47.792

90.442

0.432
  clpE Streptococcus pneumoniae D39

47.792

90.442

0.432
  clpE Streptococcus pneumoniae R6

47.792

90.442

0.432
  clpC Bacillus subtilis subsp. subtilis str. 168

44.582

92.154

0.411
  clpC Streptococcus pneumoniae Rx1

42.338

90.3

0.382
  clpC Streptococcus pneumoniae D39

42.338

90.3

0.382
  clpC Streptococcus pneumoniae TIGR4

42.18

90.3

0.381
  clpC Streptococcus thermophilus LMD-9

42.18

90.3

0.381
  clpC Streptococcus thermophilus LMG 18311

42.022

90.3

0.379
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.788

88.017

0.377
  clpC Streptococcus mutans UA159

41.586

88.16

0.367